225 pre-seed healthtech investors in the US
We list 225 pre-seed healthtech investors in the US as of November 2026: each has an SEC filing on file, and the list was last checked on 6 Nov 2026. The cities with the most head offices on this list are New York (30), San Francisco (19) and Palo Alto (17).
Top 5 pre-seed healthtech investors in the US, ranked by recent fund activity
Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when pre-seed is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.
SOSV
Type: VC firm · HQ: United States · Stages: Pre-seed · Focus: Healthtech, Deep Tech, Climate Tech, Biotech · Latest activity: Portfolio news, Nov 2026 · Fund size on file: $131M (SEC Form D, 2022)
Portfolio news dated Nov 2026; $131M fund on file (SEC Form D, 2022); states healthtech and digital health as a focus; backs pre-seed; names the US as where it invests; 8 named decision-makers on file.
Redbud VC
Type: VC firm · HQ: Columbia, MO · Stages: Pre-seed · Focus: Healthtech, Agritech, AI, Climate Tech · Latest activity: New fund, Sep 2026 · Fund size on file: $25M (SEC Form D, 2025)
Latest fund filing dated Sep 2026; $25M fund on file (SEC Form D, 2025); states healthtech and digital health as a focus; backs pre-seed; names the US as where it invests; 8 named decision-makers on file.
New Stack
Type: VC firm · HQ: Chicago, IL · Stages: Pre-seed, Seed · Focus: Healthtech, AI, Fintech, Industrial Tech · Latest activity: New fund, Sep 2026 · Fund size on file: $125M (SEC Form D, 2024)
Latest fund filing dated Sep 2026; $125M fund on file (SEC Form D, 2024); states healthtech and digital health as a focus; backs pre-seed, seed; names the US as where it invests; 3 named decision-makers on file.
1616 Ventures
Type: VC firm · HQ: Nashville, TN · Stages: Pre-seed · Focus: Healthtech, SaaS, Medtech · Latest activity: New fund, Aug 2026 · Fund size on file: $150M (SEC Form D, 2026)
Latest fund filing dated Aug 2026; $150M fund on file (SEC Form D, 2026); states healthtech and digital health as a focus; backs pre-seed; names the US as where it invests; 1 named decision-maker on file.
Avid Ventures
Type: VC firm · HQ: New York, NY · Stages: Pre-seed · Focus: Healthtech, AI, Fintech, SaaS · Latest activity: Portfolio news, Oct 2026 · Fund size on file: $75M (SEC Form D, 2021)
Portfolio news dated Oct 2026; $75M fund on file (SEC Form D, 2021); states healthtech and digital health as a focus; backs pre-seed; 2 named decision-makers on file.
First 25 of 225 pre-seed healthtech investors in the US
| Investor | Type | HQ | Stagesour research | Focusour research | Latest fund or deal | Fund sizeas filed or stated | Checked | Contacts |
|---|---|---|---|---|---|---|---|---|
| SOSV | VC firm | United States | Pre-seed | Healthtech, Deep Tech, Climate Tech, Biotech | Portfolio news, Nov 2026 | $131M (SEC Form D, 2022) | 4 Nov 2026 | 8 names · Unlock |
| Redbud VC | VC firm | Columbia, MO | Pre-seed | Healthtech, Agritech, AI, Climate Tech | New fund, Sep 2026 | $25M (SEC Form D, 2025) | 4 Nov 2026 | 8 names · Unlock |
| New Stack | VC firm | Chicago, IL | Pre-seed, Seed | Healthtech, AI, Fintech, Industrial Tech | New fund, Sep 2026 | $125M (SEC Form D, 2024) | 4 Nov 2026 | 3 names · Unlock |
| 1616 Ventures | VC firm | Nashville, TN | Pre-seed | Healthtech, SaaS, Medtech | New fund, Aug 2026 | $150M (SEC Form D, 2026) | 4 Nov 2026 | 1 name · Unlock |
| Avid Ventures | VC firm | New York, NY | Pre-seed | Healthtech, AI, Fintech, SaaS | Portfolio news, Oct 2026 | $75M (SEC Form D, 2021) | 5 Nov 2026 | 2 names, firm email · Unlock |
| Khosla Ventures | VC firm | Menlo Park, CA | Pre-seed, Seed, Series A, Growth | Healthtech, AI, Consumer, B2B | New fund, Aug 2026 | $1.9B (SEC Form D, 2025) | 4 Nov 2026 | 8 names · Unlock |
| Slauson & Co | VC firm | Los Angeles, CA | Pre-seed, Seed | Healthtech, AI, Fintech, Logistics | New deal, Sep 2026 | $100M (SEC Form D, 2023) | 5 Nov 2026 | 2 names · Unlock |
| M25 | VC firm | Chicago, IL | Pre-seed, Seed | Healthtech, AI, Generalist, Fintech | New deal, Sep 2026 | $50M (SEC Form D, 2022) | 5 Nov 2026 | 8 names · Unlock |
| LightX Capital | VC firm | Chicago, IL | Pre-seed | Healthtech, AI, Robotics, SaaS | New fund, Nov 2026 | 4 Nov 2026 | 5 names, firm email · Unlock | |
| Alliance Venture Capital | VC firm | Morton Grove, IL | Pre-seed, Seed | Healthtech, AI, SaaS | New deal, Oct 2026 | $40M (SEC Form D, 2024) | 5 Nov 2026 | 8 names, firm email · Unlock |
| Bison Ventures | VC firm | San Francisco, CA | Pre-seed, Seed, Series A, Series B | Healthtech, AI, Energy, Biotech | New fund, Oct 2026 | $160M (SEC Form D, 2025) | 4 Nov 2026 | 2 names, firm email · Unlock |
| First In Ventures | VC firm | Hobe Sound, FL | Pre-seed, Seed | Healthtech, Biotech, AI, Climate Tech | New fund, Sep 2026 | $22M (SEC Form D, 2026) | 4 Nov 2026 | 5 names, firm email · Unlock |
| Leo Capital | VC firm | San Francisco, CA | Pre-seed, Seed | Healthtech, AI, Fintech, Insurtech | New deal, Oct 2026 | $20M (SEC Form D, 2026) | 4 Nov 2026 | 8 names · Unlock |
| Cybernetix Ventures | VC firm | Boston, MA | Pre-seed, Seed, Series A | Healthtech, Robotics, Industrial Tech, Logistics | New fund, Aug 2026 | $100M (SEC Form D, 2025) | 4 Nov 2026 | 2 names · Unlock |
| January Ventures | VC firm | Wellesley Hills, MA | Pre-seed | Healthtech, AI, Future of Work, Space | New fund, Jun 2026 | $15M (SEC Form D, 2021) | 4 Nov 2026 | 7 names, firm email · Unlock |
| Heinz Ventures, LLC | VC firm | Memphis, TN | Pre-seed, Seed | Healthtech, Medtech | New deal, Aug 2026 | $10M (SEC Form D, 2024) | 4 Nov 2026 | 5 names, firm email · Unlock |
| TreeoVC | VC firm | Pompano Beach, FL | Pre-seed, Seed | Healthtech, AI, Robotics, Deep Tech | New fund, Aug 2026 | $9M (SEC Form D, 2023) | 4 Nov 2026 | 3 names, firm email · Unlock |
| Rebellion Ventures | VC firm | San Francisco, CA | Pre-seed, Seed | Healthtech, AI, Logistics, Industrial Tech | New fund, Oct 2026 | $13M (SEC Form D, 2022) | 4 Nov 2026 | 1 name · Unlock |
| Great Oaks Venture Capital | VC firm | New York, NY | Pre-seed, Seed, Series A | Healthtech, Generalist, SaaS, Fintech | Portfolio news, Sep 2026 | $20M (SEC Form ADV) | 5 Nov 2026 | 6 names · Unlock |
| Quiet Capital | VC firm | San Francisco, CA | Pre-seed | Healthtech, AI, SaaS, Fintech | New fund, Nov 2026 | $500M (SEC Form D, 2021) | 4 Nov 2026 | 3 names · Unlock |
| How Women Invest | VC firm | Oakland, CA | Pre-seed, Seed, Series A, Series B | Healthtech, AI, B2B, Climate Tech | New fund, Sep 2026 | $12M (SEC Form D, 2026) | 4 Nov 2026 | 8 names · Unlock |
| Equal Opportunity Ventures | VC firm | Cambridge, MA | Pre-seed | Healthtech, Fintech, Food and Beverage, Ecommerce | New deal, Apr 2026 | $152M (SEC Form ADV) | 5 Nov 2026 | 8 names · Unlock |
| Founder Collective | VC firm | Cambridge, MA | Pre-seed, Seed | Healthtech, AI, Ecommerce, Generalist | New deal, Jul 2026 | $95M (SEC Form D, 2023) | 5 Nov 2026 | 8 names, firm email · Unlock |
| First Round | VC firm | Philadelphia, PA | Pre-seed, Seed, Series A | Healthtech, AI, Developer Tools, Fintech | New fund, Aug 2026 | $500M (SEC Form D, 2022) | 4 Nov 2026 | 8 names · Unlock |
| Newtopia Investments | VC firm | United States | Pre-seed, Seed | Healthtech, AI, Fintech, Ecommerce | New fund, Jul 2026 | $75M (SEC Form D, 2026) | 4 Nov 2026 | 8 names, firm email · Unlock |
You are seeing 25 of 225. The full list adds 200 more investors and 1,162 named decision-makers.
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How these 225 break down
By US state
| US state | On this list | Share |
|---|---|---|
| California | 77 | 34% |
| New York | 39 | 17% |
| Massachusetts | 21 | 9% |
| Florida | 12 | 5% |
| Texas | 10 | 4% |
| Illinois | 8 | 4% |
| Pennsylvania | 7 | 3% |
| New Jersey | 4 | 2% |
| Colorado | 4 | 2% |
| Tennessee | 3 | 1% |
By type
| Type | On this list | Share |
|---|---|---|
| VC firm | 216 | 96% |
| Accelerator | 7 | 3% |
Method and limits
- Source
- All 225 rows carry an SEC filing (Form D or Form ADV). All 225 have a website we checked. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
- Inclusion rule
- Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. Sector: the firm states healthtech and digital health as a focus on its own site, or we observed it in the firm's portfolio. Stage: the firm states that it invests at pre-seed.
- Order
- Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when pre-seed is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
- Last refreshed
- November 2026. Rows on this list were checked between 4 Nov 2026 and 6 Nov 2026.
- Fill rates
- Of 225 rows: stage 225, sector 225, fund size 201, website 225. In the paid file: named decision-makers on 223 rows, firm email on 77, LinkedIn page on 127, check size on 32.
- Corrections
- Email [email protected] or use the update form. We act within 5 working days.
Questions
How many pre-seed healthtech investors in the US are there?
We list 225 as of November 2026. 140 of the 225 have a fund filing or a dated deal in the last 12 months. The cities with the most are New York (30), San Francisco (19) and Palo Alto (17).
Which pre-seed healthtech investors in the US raised a new fund in the last 12 months?
114 of the 225 have a fund filing dated in the last 12 months. The most recent on this list are Quiet Capital (Nov 2026), Branch Venture Partners (Nov 2026) and LightX Capital (Nov 2026).
What is the typical fund size of pre-seed healthtech investors in the US?
The median fund size on file for this list is $50M, across the 178 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 47 do not disclose a size there.
How do I contact pre-seed healthtech investors in the US?
The paid file holds 1,162 named decision-makers across 223 of these 225 and a firm email for 77. We publish the address a firm lists itself, never a personal email. Each free row links to a profile with the firm's website.
Where does the data on pre-seed healthtech investors in the US come from?
All 225 rows have an SEC filing on file (Form D or Form ADV). Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 6 Nov 2026 at the latest. The whole file is re-verified twice a year.
Broader lists
Healthtech venture capital firms in the US (709)Pre-seed investors in the US (549)Pre-seed healthtech investors (408)
Related lists
Seed healthtech investors in the US (437)Pre-seed AI investors in the US (403)Pre-seed SaaS investors in the US (367)Pre-seed fintech investors in the US (187)Series A healthtech investors in the US (164)Growth-stage healthtech investors in the US (121)Pre-seed deep tech investors in the US (114)Pre-seed consumer investors in the US (104)Pre-seed medtech investors in the US (95)Pre-seed hardware investors in the US (95)Pre-seed B2B investors in the US (86)Pre-seed climate tech investors in the US (84)Pre-seed biotech investors in the US (81)Pre-seed industrial tech investors in the US (79)Pre-seed robotics investors in the US (76)Pre-seed energy investors in the US (73)Series B healthtech investors in the US (69)Pre-seed developer tools investors in the US (67)
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