69 Series B healthtech investors in the US
We list 69 Series B healthtech investors in the US as of November 2026: 68 have an SEC filing on file and 1 was checked on the firm's own website or an official register, and the list was last checked on 7 Nov 2026. The cities with the most head offices on this list are New York (7), San Francisco (6) and Palo Alto (5).
Top 5 Series B healthtech investors in the US, ranked by recent fund activity
Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when Series B is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.
Alpha Partners
Type: VC firm · HQ: New York, NY · Stages: Series B, Growth · Focus: Healthtech, AI, Developer Tools, Cybersecurity · Latest activity: New fund, Oct 2026 · Fund size on file: $200M (SEC Form D, 2024)
Latest fund filing dated Oct 2026; $200M fund on file (SEC Form D, 2024); states healthtech and digital health as a focus; backs Series B, growth-stage; names the US as where it invests; 8 named decision-makers on file.
Greycroft
Type: VC firm · HQ: New York, NY · Stages: Series A, Series B, Growth · Focus: Healthtech, AI, Industrial Tech, Defense Tech · Latest activity: New deal, Oct 2026 · Fund size on file: $600M (SEC Form D, 2022)
Dated new deal in Oct 2026; $600M fund on file (SEC Form D, 2022); states healthtech and digital health as a focus; backs Series A, Series B, growth-stage; names the US as where it invests; 5 named decision-makers on file.
Translink Capital
Type: VC firm · HQ: Palo Alto, CA · Stages: Seed, Series A, Series B · Focus: Healthtech, AI, Developer Tools, Mobility · Latest activity: New fund, Sep 2026 · Fund size on file: $174M (SEC Form D, 2021)
Latest fund filing dated Sep 2026; $174M fund on file (SEC Form D, 2021); states healthtech and digital health as a focus; backs seed, Series A, Series B; names the US as where it invests; 8 named decision-makers on file.
Bison Ventures
Type: VC firm · HQ: San Francisco, CA · Stages: Pre-seed, Seed, Series A, Series B · Focus: Healthtech, AI, Energy, Biotech · Latest activity: New fund, Oct 2026 · Fund size on file: $160M (SEC Form D, 2025)
Latest fund filing dated Oct 2026; $160M fund on file (SEC Form D, 2025); states healthtech and digital health as a focus; backs pre-seed, seed, Series A; names the US as where it invests; 2 named decision-makers on file.
How Women Invest
Type: VC firm · HQ: Oakland, CA · Stages: Pre-seed, Seed, Series A, Series B · Focus: Healthtech, AI, B2B, Climate Tech · Latest activity: New fund, Sep 2026 · Fund size on file: $12M (SEC Form D, 2026)
Latest fund filing dated Sep 2026; $12M fund on file (SEC Form D, 2026); states healthtech and digital health as a focus; backs pre-seed, seed, Series A; names the US as where it invests; 8 named decision-makers on file.
First 25 of 69 Series B healthtech investors in the US
| Investor | Type | HQ | Stagesour research | Focusour research | Latest fund or deal | Fund sizeas filed or stated | Checked | Contacts |
|---|---|---|---|---|---|---|---|---|
| Alpha Partners | VC firm | New York, NY | Series B, Growth | Healthtech, AI, Developer Tools, Cybersecurity | New fund, Oct 2026 | $200M (SEC Form D, 2024) | 4 Nov 2026 | 8 names, firm email · Unlock |
| Greycroft | VC firm | New York, NY | Series A, Series B, Growth | Healthtech, AI, Industrial Tech, Defense Tech | New deal, Oct 2026 | $600M (SEC Form D, 2022) | 4 Nov 2026 | 5 names · Unlock |
| Translink Capital | VC firm | Palo Alto, CA | Seed, Series A, Series B | Healthtech, AI, Developer Tools, Mobility | New fund, Sep 2026 | $174M (SEC Form D, 2021) | 5 Nov 2026 | 8 names, firm email · Unlock |
| Bison Ventures | VC firm | San Francisco, CA | Pre-seed, Seed, Series A, Series B | Healthtech, AI, Energy, Biotech | New fund, Oct 2026 | $160M (SEC Form D, 2025) | 4 Nov 2026 | 2 names, firm email · Unlock |
| How Women Invest | VC firm | Oakland, CA | Pre-seed, Seed, Series A, Series B | Healthtech, AI, B2B, Climate Tech | New fund, Sep 2026 | $12M (SEC Form D, 2026) | 4 Nov 2026 | 8 names · Unlock |
| Lightspeed Venture Partners | VC firm | Menlo Park, CA | Seed, Series A, Series B, Growth | Healthtech, AI, Gaming, SaaS | New fund, Jul 2026 | $1.2B (SEC Form D, 2024) | 4 Nov 2026 | 8 names · Unlock |
| Ansa | VC firm | New York, NY | Series A, Series B, Growth | Healthtech, AI, Cybersecurity, Media | New fund, May 2026 | $200M (SEC Form D, 2026) | 4 Nov 2026 | 4 names, firm email · Unlock |
| FLF Accelerate | VC firm | Tampa, FL | Pre-seed, Seed, Series A, Series B | Healthtech, AI, Fintech, Media | New fund, Sep 2026 | $5M (SEC Form D, 2026) | 4 Nov 2026 | 8 names · Unlock |
| SignalFire | VC firm | San Francisco, CA | Seed, Series A, Series B, Growth | Healthtech, AI, Developer Tools, B2B | New fund, May 2026 | $357M (SEC Form D, 2021) | 4 Nov 2026 | 8 names · Unlock |
| Arboretum Ventures | VC firm | Ann Arbor, MI | Series A, Series B | Healthtech, Biotech, Medtech | Portfolio news, Mar 2026 | $250M (SEC Form D, 2022) | 5 Nov 2026 | 7 names · Unlock |
| True Beauty Ventures | VC firm | Palm Beach Gardens, FL | Seed, Series A, Series B | Healthtech, Consumer, CPG | New fund, Oct 2026 | $308M (SEC Form D, 2022) | 4 Nov 2026 | 8 names, firm email · Unlock |
| IVP: Venture capital for the Exceptional | VC firm | Menlo Park, CA | Series B, Growth | Healthtech, AI, Developer Tools, SaaS | New fund, Oct 2026 | $60M (SEC Form D, 2026) | 4 Nov 2026 | 8 names · Unlock |
| Menlo Ventures | VC firm | Menlo Park, CA | Pre-seed, Seed, Series A, Series B, Growth | Healthtech, AI, Media, Robotics | New fund, Sep 2026 | $800M (SEC Form D, 2025) | 4 Nov 2026 | 8 names · Unlock |
| Sandbox Clinical Ventures | VC firm | Chicago, IL | Seed, Series A, Series B, Growth | Healthtech, Insurtech, AI, Fintech | New fund, Sep 2026 | $100M (SEC Form D, 2021) | 4 Nov 2026 | 8 names, firm email · Unlock |
| Cultivation Capital | VC firm | St. Louis, MO | Seed, Series A, Series B | Healthtech, Biotech, SaaS, Agritech | New fund, Sep 2026 | $100M (SEC Form D, 2022) | 4 Nov 2026 | 8 names · Unlock |
| Antler | Accelerator | New York, NY | Pre-seed, Seed, Series A, Series B, Growth | Healthtech, AI, Biotech, Consumer | New deal, Aug 2026 | $90M (SEC Form D, 2023) | 4 Nov 2026 | 8 names · Unlock |
| Andreessen Horowitz (a16z) | VC firm | Menlo Park, CA | Seed, Series A, Series B, Growth | Healthtech, AI, Defense Tech, Consumer | New fund, Aug 2026 | 4 Nov 2026 | 2 names · Unlock | |
| Overlap Holdings | VC firm | Hicksville, NY | Seed, Series A, Series B | Healthtech, AI, Energy, Climate Tech | New fund, Oct 2026 | $16M (SEC Form D, 2023) | 4 Nov 2026 | 8 names · Unlock |
| Claritas Signal Partners | VC firm | Nashville, TN | Seed, Series A, Series B, Growth | Healthtech, AI, Media, Developer Tools | New deal, Aug 2026 | $14M (SEC Form D, 2021) | 5 Nov 2026 | 8 names · Unlock |
| Calculus VC | VC firm | Foster City, CA | Series A, Series B | Healthtech, AI, Deep Tech, Industrial Tech | New deal, Aug 2026 | $1M (SEC Form D, 2025) | 4 Nov 2026 | 1 name, firm email · Unlock |
| Cornucopian Capital | VC firm | Montclair, NJ | Pre-seed, Seed, Series A, Series B | Healthtech, AI, Medtech, Biotech | New fund, Aug 2026 | $12M (SEC Form D, 2024) | 4 Nov 2026 | 1 name · Unlock |
| B Capital | VC firm | Manhattan Beach, CA | Seed, Series A, Series B, Growth | Healthtech, AI, Fintech, Biotech | New fund, Jul 2025 | $307M (SEC Form D, 2023) | 4 Nov 2026 | 8 names, firm email · Unlock |
| Celesta Capital | VC firm | San Mateo, CA | Seed, Series A, Series B | Healthtech, AI, Deep Tech, Biotech | New fund, Sep 2025 | $102M (SEC Form D, 2024) | 4 Nov 2026 | 8 names, firm email · Unlock |
| S3 Ventures | VC firm | Austin, TX | Seed, Series A, Series B | Healthtech, Developer Tools, Medtech, SaaS | New fund, Sep 2025 | $150M (SEC Form D, 2022) | 4 Nov 2026 | 1 name · Unlock |
| Acrew Diversify Capital | VC firm | San Francisco, CA | Seed, Series A, Series B, Growth | Healthtech, Fintech, AI, Cybersecurity | New deal, Aug 2026 | 5 Nov 2026 | 8 names, firm email · Unlock |
You are seeing 25 of 69. The full list adds 44 more investors and 390 named decision-makers.
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How these 69 break down
By US state
| US state | On this list | Share |
|---|---|---|
| California | 22 | 32% |
| New York | 10 | 14% |
| Massachusetts | 7 | 10% |
| Florida | 3 | 4% |
| Tennessee | 3 | 4% |
| New Jersey | 3 | 4% |
| Texas | 3 | 4% |
| Michigan | 2 | 3% |
| Illinois | 2 | 3% |
| Pennsylvania | 2 | 3% |
By type
| Type | On this list | Share |
|---|---|---|
| VC firm | 67 | 97% |
| Accelerator | 1 | 1% |
| Corporate VC | 1 | 1% |
Method and limits
- Source
- 68 of the 69 rows carry an SEC filing (Form D or Form ADV). All 69 have a website we checked. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
- Inclusion rule
- Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. Sector: the firm states healthtech and digital health as a focus on its own site, or we observed it in the firm's portfolio. Stage: the firm states that it invests at Series B.
- Order
- Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when Series B is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
- Last refreshed
- November 2026. Rows on this list were checked between 4 Nov 2026 and 7 Nov 2026.
- Fill rates
- Of 69 rows: stage 69, sector 69, fund size 57, website 69. In the paid file: named decision-makers on 66 rows, firm email on 28, LinkedIn page on 45, check size on 7.
- Corrections
- Email [email protected] or use the update form. We act within 5 working days.
Questions
How many Series B healthtech investors in the US are there?
We list 69 as of November 2026. 38 of the 69 have a fund filing or a dated deal in the last 12 months. The cities with the most are New York (7), San Francisco (6) and Palo Alto (5).
Which Series B healthtech investors in the US raised a new fund in the last 12 months?
27 of the 69 have a fund filing dated in the last 12 months. The most recent on this list are IVP: Venture capital for the Exceptional (Oct 2026), True Beauty Ventures (Oct 2026) and Bison Ventures (Oct 2026).
What is the typical fund size of Series B healthtech investors in the US?
The median fund size on file for this list is $90M, across the 47 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 22 do not disclose a size there.
How do I contact Series B healthtech investors in the US?
The paid file holds 390 named decision-makers across 66 of these 69 and a firm email for 28. We publish the address a firm lists itself, never a personal email. Each free row links to a profile with the firm's website.
Where does the data on Series B healthtech investors in the US come from?
68 of the 69 rows have an SEC filing on file (Form D or Form ADV) and 1 was checked on the firm's own website or an official register. Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 7 Nov 2026 at the latest. The whole file is re-verified twice a year.
Broader lists
Healthtech venture capital firms in the US (709)Series B investors in the US (165)Series B healthtech investors (160)
Related lists
Seed healthtech investors in the US (437)Pre-seed healthtech investors in the US (225)Series A healthtech investors in the US (164)Series B AI investors in the US (126)Growth-stage healthtech investors in the US (121)Series B SaaS investors in the US (108)Series B fintech investors in the US (59)Series B deep tech investors in the US (41)Series B cybersecurity investors in the US (37)Series B medtech investors in the US (36)Series B biotech investors in the US (34)Series B energy investors in the US (29)Series B industrial tech investors in the US (29)Series B consumer investors in the US (29)Series B hardware investors in the US (28)Series B B2B investors in the US (27)Series B climate tech investors in the US (27)Series B developer tools investors in the US (21)
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