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Updated November 2026

164 Series A healthtech investors in the US

We list 164 Series A healthtech investors in the US as of November 2026: 162 have an SEC filing on file and 2 were checked on the firm's own website or an official register, and the list was last checked on 7 Nov 2026. The cities with the most head offices on this list are San Francisco (15), New York (14) and Palo Alto (13).

164investors
86with a fund filing or dated deal in the last 12 months
$100Mmedian fund size on file (SEC Form D, 108 firms)
898named decision-makers on file

Top 5 Series A healthtech investors in the US, ranked by recent fund activity

Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when Series A is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.

  1. Greycroft

    Type: VC firm · HQ: New York, NY · Stages: Series A, Series B, Growth · Focus: Healthtech, AI, Industrial Tech, Defense Tech · Latest activity: New deal, Oct 2026 · Fund size on file: $600M (SEC Form D, 2022)

    Dated new deal in Oct 2026; $600M fund on file (SEC Form D, 2022); states healthtech and digital health as a focus; backs Series A, Series B, growth-stage; names the US as where it invests; 5 named decision-makers on file.

  2. Mindset Consulting (US)

    Type: VC firm · HQ: San Francisco, CA · Stages: Seed, Series A · Focus: Healthtech, B2B, AI, Fintech · Latest activity: Portfolio news, Sep 2026 · Private fund assets: $129M (SEC Form ADV)

    Portfolio news dated Sep 2026; $129M on file (SEC Form ADV); states healthtech and digital health as a focus; backs seed, Series A; names the US as where it invests; 7 named decision-makers on file.

  3. Flyover Capital

    Type: VC firm · HQ: Kansas City, MO · Stages: Seed, Series A · Focus: Healthtech, AI, Fintech, SaaS · Latest activity: New fund, Oct 2026 · Fund size on file: $75M (SEC Form D, 2026)

    Latest fund filing dated Oct 2026; $75M fund on file (SEC Form D, 2026); states healthtech and digital health as a focus; backs seed, Series A; names the US as where it invests; 8 named decision-makers on file.

  4. Khosla Ventures

    Type: VC firm · HQ: Menlo Park, CA · Stages: Pre-seed, Seed, Series A, Growth · Focus: Healthtech, AI, Consumer, B2B · Latest activity: New fund, Aug 2026 · Fund size on file: $1.9B (SEC Form D, 2025)

    Latest fund filing dated Aug 2026; $1.9B fund on file (SEC Form D, 2025); states healthtech and digital health as a focus; backs pre-seed, seed, Series A; names the US as where it invests; 8 named decision-makers on file.

  5. Translink Capital

    Type: VC firm · HQ: Palo Alto, CA · Stages: Seed, Series A, Series B · Focus: Healthtech, AI, Developer Tools, Mobility · Latest activity: New fund, Sep 2026 · Fund size on file: $174M (SEC Form D, 2021)

    Latest fund filing dated Sep 2026; $174M fund on file (SEC Form D, 2021); states healthtech and digital health as a focus; backs seed, Series A, Series B; names the US as where it invests; 8 named decision-makers on file.

First 25 of 164 Series A healthtech investors in the US

InvestorTypeHQStagesour researchFocusour researchLatest fund or dealFund sizeas filed or statedCheckedContacts
GreycroftVC firmNew York, NYSeries A, Series B, GrowthHealthtech, AI, Industrial Tech, Defense TechNew deal, Oct 2026$600M (SEC Form D, 2022)4 Nov 20265 names · Unlock
Mindset Consulting (US)VC firmSan Francisco, CASeed, Series AHealthtech, B2B, AI, FintechPortfolio news, Sep 2026$129M (SEC Form ADV)5 Nov 20267 names · Unlock
Flyover CapitalVC firmKansas City, MOSeed, Series AHealthtech, AI, Fintech, SaaSNew fund, Oct 2026$75M (SEC Form D, 2026)4 Nov 20268 names, firm email · Unlock
Khosla VenturesVC firmMenlo Park, CAPre-seed, Seed, Series A, GrowthHealthtech, AI, Consumer, B2BNew fund, Aug 2026$1.9B (SEC Form D, 2025)4 Nov 20268 names · Unlock
Translink CapitalVC firmPalo Alto, CASeed, Series A, Series BHealthtech, AI, Developer Tools, MobilityNew fund, Sep 2026$174M (SEC Form D, 2021)5 Nov 20268 names, firm email · Unlock
Bison VenturesVC firmSan Francisco, CAPre-seed, Seed, Series A, Series BHealthtech, AI, Energy, BiotechNew fund, Oct 2026$160M (SEC Form D, 2025)4 Nov 20262 names, firm email · Unlock
Cybernetix VenturesVC firmBoston, MAPre-seed, Seed, Series AHealthtech, Robotics, Industrial Tech, LogisticsNew fund, Aug 2026$100M (SEC Form D, 2025)4 Nov 20262 names · Unlock
FelicisVC firmMenlo Park, CASeed, Series AHealthtech, AI, Developer Tools, CybersecurityNew deal, Oct 2026$900M (SEC Form D, 2025)5 Nov 20268 names · Unlock
Great Oaks Venture CapitalVC firmNew York, NYPre-seed, Seed, Series AHealthtech, Generalist, SaaS, FintechPortfolio news, Sep 2026$20M (SEC Form ADV)5 Nov 20266 names · Unlock
Javelin Venture PartnersVC firmSan Francisco, CASeed, Series AHealthtech, AI, SaaS, FintechNew fund, Aug 2026$200M (SEC Form D, 2026)4 Nov 20268 names, firm email · Unlock
Motley Fool VenturesVC firmAlexandria, VASeries AHealthtech, Fintech, AI, ProptechPortfolio news, Oct 2026$300M (SEC Form D, 2022)5 Nov 20268 names · Unlock
Distributed VenturesVC firmChicago, ILSeed, Series AHealthtech, Fintech, Insurtech, AINew deal, Jul 2026$90M (SEC Form D, 2021)5 Nov 20265 names, firm email · Unlock
SixThirty Ventures, LLCVC firmClayton, MOSeed, Series AHealthtech, Fintech, AI, InsurtechNew deal, Sep 2026$134M (SEC Form ADV)5 Nov 20268 names, firm email · Unlock
How Women InvestVC firmOakland, CAPre-seed, Seed, Series A, Series BHealthtech, AI, B2B, Climate TechNew fund, Sep 2026$12M (SEC Form D, 2026)4 Nov 20268 names · Unlock
Promus VenturesVC firmChicago, ILSeed, Series AHealthtech, Deep Tech, Space, Industrial TechPortfolio news, Sep 2026$203M (SEC Form ADV)5 Nov 2026firm email · Unlock
First RoundVC firmPhiladelphia, PAPre-seed, Seed, Series AHealthtech, AI, Developer Tools, FintechNew fund, Aug 2026$500M (SEC Form D, 2022)4 Nov 20268 names · Unlock
Kalos VenturesVC firmBrooklyn, NYSeed, Series AHealthtech, Future of Work, Edtech, HardwareNew deal, Aug 2026$75M (SEC Form D, 2024)4 Nov 20266 names, firm email · Unlock
Lightspeed Venture PartnersVC firmMenlo Park, CASeed, Series A, Series B, GrowthHealthtech, AI, Gaming, SaaSNew fund, Jul 2026$1.2B (SEC Form D, 2024)4 Nov 20268 names · Unlock
DeepWork CapitalVC firmOrlando, FLSeed, Series AHealthtech, Biotech, Fintech, AINew deal, Jun 2026$100M (SEC Form D, 2023)5 Nov 20268 names · Unlock
AnsaVC firmNew York, NYSeries A, Series B, GrowthHealthtech, AI, Cybersecurity, MediaNew fund, May 2026$200M (SEC Form D, 2026)4 Nov 20264 names, firm email · Unlock
Winter Street VenturesVC firmBoston, MASeed, Series AHealthtech, AI, MedtechNew fund, Jun 2026$75M (SEC Form D, 2026)4 Nov 20262 names, firm email · Unlock
Draper AssociatesVC firmSan Mateo, CAPre-seed, Seed, Series AHealthtech, AI, Fintech, MobilityNew fund, Oct 2026$301M (SEC Form D, 2025)4 Nov 20268 names · Unlock
FLF AccelerateVC firmTampa, FLPre-seed, Seed, Series A, Series BHealthtech, AI, Fintech, MediaNew fund, Sep 2026$5M (SEC Form D, 2026)4 Nov 20268 names · Unlock
SignalFireVC firmSan Francisco, CASeed, Series A, Series B, GrowthHealthtech, AI, Developer Tools, B2BNew fund, May 2026$357M (SEC Form D, 2021)4 Nov 20268 names · Unlock
Electric CapitalVC firmPalo Alto, CAPre-seed, Seed, Series AHealthtech, Crypto and Web3, AI, FintechNew fund, Sep 2026$532M (SEC Form D, 2021)4 Nov 20268 names, firm email · Unlock

You are seeing 25 of 164. The full list adds 139 more investors and 898 named decision-makers.

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How these 164 break down

By US state

US stateOn this listShare
California5936%
New York1811%
Massachusetts95%
Florida95%
Texas95%
Illinois85%
Pennsylvania85%
Tennessee53%
New Jersey42%
Missouri32%

By type

TypeOn this listShare
VC firm16198%
Corporate VC21%

Method and limits

Source
162 of the 164 rows carry an SEC filing (Form D or Form ADV). All 164 have a website we checked. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
Inclusion rule
Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. Sector: the firm states healthtech and digital health as a focus on its own site, or we observed it in the firm's portfolio. Stage: the firm states that it invests at Series A.
Order
Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when Series A is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
Last refreshed
November 2026. Rows on this list were checked between 4 Nov 2026 and 7 Nov 2026.
Fill rates
Of 164 rows: stage 164, sector 164, fund size 141, website 164. In the paid file: named decision-makers on 157 rows, firm email on 63, LinkedIn page on 107, check size on 21.
Corrections
Email [email protected] or use the update form. We act within 5 working days.

How we verify

Questions

How many Series A healthtech investors in the US are there?

We list 164 as of November 2026. 86 of the 164 have a fund filing or a dated deal in the last 12 months. The cities with the most are San Francisco (15), New York (14) and Palo Alto (13).

Which Series A healthtech investors in the US raised a new fund in the last 12 months?

57 of the 164 have a fund filing dated in the last 12 months. The most recent on this list are 25Madison Ventures (Oct 2026), Draper Associates (Oct 2026) and True Beauty Ventures (Oct 2026).

What is the typical fund size of Series A healthtech investors in the US?

The median fund size on file for this list is $100M, across the 108 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 56 do not disclose a size there.

How do I contact Series A healthtech investors in the US?

The paid file holds 898 named decision-makers across 157 of these 164 and a firm email for 63. We publish the address a firm lists itself, never a personal email. Each free row links to a profile with the firm's website.

Where does the data on Series A healthtech investors in the US come from?

162 of the 164 rows have an SEC filing on file (Form D or Form ADV) and 2 were checked on the firm's own website or an official register. Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 7 Nov 2026 at the latest. The whole file is re-verified twice a year.

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