95 pre-seed medtech investors in the US
We list 95 pre-seed medtech investors in the US as of November 2026: each has an SEC filing on file, and the list was last checked on 6 Nov 2026. The cities with the most head offices on this list are New York (16), San Francisco (9) and Palo Alto (8).
Top 5 pre-seed medtech investors in the US, ranked by recent fund activity
Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when pre-seed is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.
Heinz Ventures, LLC
Type: VC firm · HQ: Memphis, TN · Stages: Pre-seed, Seed · Focus: Medtech, Healthtech · Latest activity: New deal, Aug 2026 · Fund size on file: $10M (SEC Form D, 2024)
Dated new deal in Aug 2026; $10M fund on file (SEC Form D, 2024); 100% of its observed portfolio is medtech and medical devices; backs pre-seed, seed; names the US as where it invests; 5 named decision-makers on file.
Equal Opportunity Ventures
Type: VC firm · HQ: Cambridge, MA · Stages: Pre-seed · Focus: Medtech, Healthtech, Fintech, Food and Beverage · Latest activity: New deal, Apr 2026 · Private fund assets: $152M (SEC Form ADV)
Dated new deal in Apr 2026; $152M on file (SEC Form ADV); 50% of its observed portfolio is medtech and medical devices; backs pre-seed; names the US as where it invests; 8 named decision-makers on file.
1616 Ventures
Type: VC firm · HQ: Nashville, TN · Stages: Pre-seed · Focus: Medtech, Healthtech, SaaS · Latest activity: New fund, Aug 2026 · Fund size on file: $150M (SEC Form D, 2026)
Latest fund filing dated Aug 2026; $150M fund on file (SEC Form D, 2026); 31% of its observed portfolio is medtech and medical devices; backs pre-seed; names the US as where it invests; 1 named decision-maker on file.
Meridian Street
Type: VC firm · HQ: New York, NY · Stages: Pre-seed · Focus: Medtech, Healthtech, AI, Fintech · Latest activity: New fund, Aug 2026 · Fund size on file: $85M (SEC Form D, 2026)
Latest fund filing dated Aug 2026; $85M fund on file (SEC Form D, 2026); 48% of its observed portfolio is medtech and medical devices; backs pre-seed; 8 named decision-makers on file.
Khosla Ventures
Type: VC firm · HQ: Menlo Park, CA · Stages: Pre-seed, Seed, Series A, Growth · Focus: Medtech, AI, Consumer, B2B · Latest activity: New fund, Aug 2026 · Fund size on file: $1.9B (SEC Form D, 2025)
Latest fund filing dated Aug 2026; $1.9B fund on file (SEC Form D, 2025); states medtech and medical devices as a focus; backs pre-seed, seed, Series A; names the US as where it invests; 8 named decision-makers on file.
First 25 of 95 pre-seed medtech investors in the US
| Investor | Type | HQ | Stagesour research | Focusour research | Latest fund or deal | Fund sizeas filed or stated | Checked | Contacts |
|---|---|---|---|---|---|---|---|---|
| Heinz Ventures, LLC | VC firm | Memphis, TN | Pre-seed, Seed | Medtech, Healthtech | New deal, Aug 2026 | $10M (SEC Form D, 2024) | 4 Nov 2026 | 5 names, firm email · Unlock |
| Equal Opportunity Ventures | VC firm | Cambridge, MA | Pre-seed | Medtech, Healthtech, Fintech, Food and Beverage | New deal, Apr 2026 | $152M (SEC Form ADV) | 5 Nov 2026 | 8 names · Unlock |
| 1616 Ventures | VC firm | Nashville, TN | Pre-seed | Medtech, Healthtech, SaaS | New fund, Aug 2026 | $150M (SEC Form D, 2026) | 4 Nov 2026 | 1 name · Unlock |
| Meridian Street | VC firm | New York, NY | Pre-seed | Medtech, Healthtech, AI, Fintech | New fund, Aug 2026 | $85M (SEC Form D, 2026) | 4 Nov 2026 | 8 names · Unlock |
| Khosla Ventures | VC firm | Menlo Park, CA | Pre-seed, Seed, Series A, Growth | Medtech, AI, Consumer, B2B | New fund, Aug 2026 | $1.9B (SEC Form D, 2025) | 4 Nov 2026 | 8 names · Unlock |
| January Ventures | VC firm | Wellesley Hills, MA | Pre-seed | Medtech, Healthtech, AI, Future of Work | New fund, Jun 2026 | $15M (SEC Form D, 2021) | 4 Nov 2026 | 7 names, firm email · Unlock |
| Cybernetix Ventures | VC firm | Boston, MA | Pre-seed, Seed, Series A | Medtech, Robotics, Industrial Tech, Logistics | New fund, Aug 2026 | $100M (SEC Form D, 2025) | 4 Nov 2026 | 2 names · Unlock |
| Avid Ventures | VC firm | New York, NY | Pre-seed | Medtech, AI, Fintech, Healthtech | Portfolio news, Oct 2026 | $75M (SEC Form D, 2021) | 5 Nov 2026 | 2 names, firm email · Unlock |
| Great Oaks Venture Capital | VC firm | New York, NY | Pre-seed, Seed, Series A | Medtech, Healthtech, Generalist, SaaS | Portfolio news, Sep 2026 | $20M (SEC Form ADV) | 5 Nov 2026 | 6 names · Unlock |
| 25Madison Ventures | VC firm | New York, NY | Pre-seed, Seed, Series A | Medtech, Healthtech, AI, Logistics | New fund, Oct 2026 | $50M (SEC Form D, 2026) | 4 Nov 2026 | 8 names, firm email · Unlock |
| How Women Invest | VC firm | Oakland, CA | Pre-seed, Seed, Series A, Series B | Medtech, Healthtech, AI, B2B | New fund, Sep 2026 | $12M (SEC Form D, 2026) | 4 Nov 2026 | 8 names · Unlock |
| Capital F | VC firm | Mill Valley, CA | Pre-seed, Seed | Medtech, AI, Healthtech, Climate Tech | New fund, Jul 2026 | $17M (SEC Form D, 2024) | 4 Nov 2026 | 2 names, firm email · Unlock |
| Averin | VC firm | Andover, MA | Pre-seed | Medtech, Healthtech, AI, Robotics | New fund, Mar 2026 | $350M (SEC Form D, 2026) | 4 Nov 2026 | 7 names · Unlock |
| Actions | VC firm | New York, NY | Pre-seed, Seed | Medtech, Healthtech, Fintech, AI | New fund, Dec 2025 | $35M (SEC Form D, 2025) | 4 Nov 2026 | 8 names, firm email · Unlock |
| Voltage Ventures | VC firm | Portland, ME | Pre-seed | Medtech, Healthtech, Biotech | New fund, Jul 2026 | $18M (SEC Form D, 2026) | 4 Nov 2026 | 4 names · Unlock |
| 3i Partners | VC firm | Los Altos, CA | Pre-seed, Seed | Medtech, Mobility, Healthtech, Deep Tech | New fund, May 2026 | $24M (SEC Form D, 2025) | 5 Nov 2026 | 8 names · Unlock |
| First Round | VC firm | Philadelphia, PA | Pre-seed, Seed, Series A | Medtech, AI, Developer Tools, Fintech | New fund, Aug 2026 | $500M (SEC Form D, 2022) | 4 Nov 2026 | 8 names · Unlock |
| W Health Ventures | VC firm | Boston, MA | Pre-seed | Medtech, Healthtech, AI, Semiconductor | New fund, Dec 2025 | $45M (SEC Form D, 2025) | 4 Nov 2026 | 8 names, firm email · Unlock |
| Zeal Capital Partners | VC firm | Washington, DC | Pre-seed, Seed | Medtech, Fintech, Healthtech, Edtech | New deal, Aug 2026 | $120M (SEC Form D, 2023) | 5 Nov 2026 | 2 names · Unlock |
| Seae Ventures | VC firm | Miami, FL | Pre-seed, Seed | Medtech, Healthtech | New fund, Feb 2026 | $107M (SEC Form D, 2020) | 4 Nov 2026 | 8 names · Unlock |
| Wavemaker Three-Sixty Health | VC firm | Pasadena, CA | Pre-seed, Seed, Series A | Medtech, Healthtech, AI | New fund, Dec 2024 | $100M (SEC Form D, 2021) | 5 Nov 2026 | 8 names · Unlock |
| Julian Capital: Deeptech Seed Fund | VC firm | San Francisco, CA | Pre-seed, Seed | Medtech, Energy, Deep Tech, Healthtech | New fund, Aug 2026 | $51M (SEC Form D, 2026) | 4 Nov 2026 | 5 names · Unlock |
| Magnify Ventures | VC firm | Santa Monica, CA | Pre-seed, Seed | Medtech, Healthtech, AI, Consumer | New fund, Jul 2026 | $50M (SEC Form D, 2021) | 4 Nov 2026 | 7 names, firm email · Unlock |
| Headwater Ventures | VC firm | Minneapolis, MN | Pre-seed, Seed | Medtech, Healthtech, AI, Insurtech | New fund, Jun 2026 | $11M (SEC Form D, 2025) | 4 Nov 2026 | 1 name · Unlock |
| Charge | VC firm | New York, NY | Pre-seed | Medtech, AI, Healthtech, Marketing Tech | New fund, Jun 2026 | $30M (SEC Form D, 2022) | 4 Nov 2026 | 3 names · Unlock |
You are seeing 25 of 95. The full list adds 70 more investors and 465 named decision-makers.
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How these 95 break down
By US state
| US state | On this list | Share |
|---|---|---|
| California | 30 | 32% |
| New York | 19 | 20% |
| Massachusetts | 9 | 9% |
| Pennsylvania | 4 | 4% |
| Texas | 4 | 4% |
| Florida | 3 | 3% |
| Tennessee | 2 | 2% |
| Minnesota | 2 | 2% |
| Washington | 2 | 2% |
| New Jersey | 2 | 2% |
By type
| Type | On this list | Share |
|---|---|---|
| VC firm | 92 | 97% |
| Accelerator | 3 | 3% |
Method and limits
- Source
- All 95 rows carry an SEC filing (Form D or Form ADV). All 95 have a website we checked. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
- Inclusion rule
- Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. Sector: the firm states medtech and medical devices as a focus on its own site, or we observed it in the firm's portfolio. Stage: the firm states that it invests at pre-seed.
- Order
- Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when pre-seed is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
- Last refreshed
- November 2026. Rows on this list were checked between 4 Nov 2026 and 6 Nov 2026.
- Fill rates
- Of 95 rows: stage 95, sector 95, fund size 83, website 95. In the paid file: named decision-makers on 94 rows, firm email on 28, LinkedIn page on 53, check size on 11.
- Corrections
- Email [email protected] or use the update form. We act within 5 working days.
Questions
How many pre-seed medtech investors in the US are there?
We list 95 as of November 2026. 58 of the 95 have a fund filing or a dated deal in the last 12 months. The cities with the most are New York (16), San Francisco (9) and Palo Alto (8).
Which pre-seed medtech investors in the US raised a new fund in the last 12 months?
49 of the 95 have a fund filing dated in the last 12 months. The most recent on this list are 25Madison Ventures (Oct 2026), Dorm Room (Oct 2026) and How Women Invest (Sep 2026).
What is the typical fund size of pre-seed medtech investors in the US?
The median fund size on file for this list is $50M, across the 71 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 24 do not disclose a size there.
How do I contact pre-seed medtech investors in the US?
The paid file holds 465 named decision-makers across 94 of these 95 and a firm email for 28. We publish the address a firm lists itself, never a personal email. Each free row links to a profile with the firm's website.
Where does the data on pre-seed medtech investors in the US come from?
All 95 rows have an SEC filing on file (Form D or Form ADV). Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 6 Nov 2026 at the latest. The whole file is re-verified twice a year.
Broader lists
Medtech venture capital firms in the US (350)Pre-seed investors in the US (549)Pre-seed medtech investors (129)
Related lists
Pre-seed AI investors in the US (403)Pre-seed SaaS investors in the US (367)Pre-seed healthtech investors in the US (225)Seed medtech investors in the US (205)Pre-seed fintech investors in the US (187)Pre-seed deep tech investors in the US (114)Pre-seed consumer investors in the US (104)Pre-seed hardware investors in the US (95)Pre-seed B2B investors in the US (86)Pre-seed climate tech investors in the US (84)Pre-seed biotech investors in the US (81)Pre-seed industrial tech investors in the US (79)Series A medtech investors in the US (76)Pre-seed robotics investors in the US (76)Pre-seed energy investors in the US (73)Growth-stage medtech investors in the US (69)Pre-seed developer tools investors in the US (67)Pre-seed cybersecurity investors in the US (60)
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