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Updated November 2026

350 medtech venture capital firms in the US

We list 350 medtech venture capital firms in the US as of November 2026: 348 have an SEC filing on file and 2 were checked on the firm's own website or an official register, and the list was last checked on 6 Nov 2026. The cities with the most head offices on this list are New York (47), San Francisco (25) and Boston (19).

350firms
178with a fund filing or dated deal in the last 12 months
$60Mmedian fund size on file (SEC Form D, 243 firms)
1,731named decision-makers on file

Top 10 medtech venture capital firms in the US, ranked by recent fund activity

Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (35: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (25; half of that when the sector is stated only), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (15) and completeness of the public record (10). Regional focus is our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.

  1. Frist Cressey Ventures

    Type: VC firm · HQ: Nashville, TN · Focus: Medtech, Healthtech · Latest activity: New deal, Oct 2026 · Fund size on file: $400M (SEC Form D, 2025)

    Dated new deal in Oct 2026; $400M fund on file (SEC Form D, 2025); 64% of its observed portfolio is medtech and medical devices; names the US as where it invests; 8 named decision-makers on file.

  2. Heinz Ventures, LLC

    Type: VC firm · HQ: Memphis, TN · Stages: Pre-seed, Seed · Focus: Medtech, Healthtech · Latest activity: New deal, Aug 2026 · Fund size on file: $10M (SEC Form D, 2024)

    Dated new deal in Aug 2026; $10M fund on file (SEC Form D, 2024); 100% of its observed portfolio is medtech and medical devices; names the US as where it invests; 5 named decision-makers on file.

  3. JSTAR Capital

    Type: VC firm · HQ: Austin, TX · Stages: Growth · Focus: Medtech, Healthtech, AI, Fintech · Latest activity: New fund, Aug 2026 · Fund size on file: $100M (SEC Form D, 2025)

    Latest fund filing dated Aug 2026; $100M fund on file (SEC Form D, 2025); 62% of its observed portfolio is medtech and medical devices; 8 named decision-makers on file.

  4. Khosla Ventures

    Type: VC firm · HQ: Menlo Park, CA · Stages: Pre-seed, Seed, Series A, Growth · Focus: Medtech, AI, Consumer, B2B · Latest activity: New fund, Aug 2026 · Fund size on file: $1.9B (SEC Form D, 2025)

    Latest fund filing dated Aug 2026; $1.9B fund on file (SEC Form D, 2025); states medtech and medical devices as a focus; names the US as where it invests; 8 named decision-makers on file.

  5. Digitalis Ventures

    Type: VC firm · HQ: New York, NY · Stages: Seed · Focus: Medtech, Healthtech, Biotech · Latest activity: Portfolio news, Nov 2026 · Private fund assets: $862M (SEC Form ADV)

    Portfolio news dated Nov 2026; $862M on file (SEC Form ADV); states medtech and medical devices as a focus; names the US as where it invests; 8 named decision-makers on file.

  6. Agetech Capital

    Type: VC firm · HQ: Austin, TX · Focus: Medtech, Healthtech, AI, Fintech · Latest activity: New fund, Sep 2026 · Fund size on file: $3M (SEC Form D, 2026)

    Latest fund filing dated Sep 2026; $3M fund on file (SEC Form D, 2026); 50% of its observed portfolio is medtech and medical devices; names the US as where it invests; 6 named decision-makers on file.

  7. Gore Range Capital

    Type: VC firm · HQ: Southlake, TX · Stages: Seed · Focus: Medtech, Healthtech, Biotech · Latest activity: New deal, Aug 2026 · Fund size on file: $250M (SEC Form D, 2026)

    Dated new deal in Aug 2026; $250M fund on file (SEC Form D, 2026); states medtech and medical devices as a focus; names the US as where it invests; 1 named decision-maker on file.

  8. Town Hall Ventures

    Type: VC firm · HQ: New York, NY · Stages: Growth · Focus: Medtech, Healthtech, Impact · Latest activity: New deal, Sep 2026 · Fund size on file: $400M (SEC Form D, 2025)

    Dated new deal in Sep 2026; $400M fund on file (SEC Form D, 2025); states medtech and medical devices as a focus; names the US as where it invests; 8 named decision-makers on file.

  9. Echo Health Ventures

    Type: Corporate VC · HQ: Durham, NC · Stages: Growth · Focus: Medtech, Healthtech · Latest activity: Portfolio news, Sep 2026 · Private fund assets: $518M (SEC Form ADV)

    Portfolio news dated Sep 2026; $518M on file (SEC Form ADV); 77% of its observed portfolio is medtech and medical devices; 2 named decision-makers on file.

  10. Health Velocity Capital

    Type: VC firm · HQ: San Mateo, CA · Focus: Medtech, Healthtech, SaaS · Latest activity: New fund, Aug 2026 · Fund size on file: $300M (SEC Form D, 2025)

    Latest fund filing dated Aug 2026; $300M fund on file (SEC Form D, 2025); states medtech and medical devices as a focus; names the US as where it invests; 5 named decision-makers on file.

First 25 of 350 medtech venture capital firms in the US

InvestorTypeHQStagesour researchFocusour researchLatest fund or dealFund sizeas filed or statedCheckedContacts
Frist Cressey VenturesVC firmNashville, TNMedtech, HealthtechNew deal, Oct 2026$400M (SEC Form D, 2025)4 Nov 20268 names · Unlock
Heinz Ventures, LLCVC firmMemphis, TNPre-seed, SeedMedtech, HealthtechNew deal, Aug 2026$10M (SEC Form D, 2024)4 Nov 20265 names, firm email · Unlock
JSTAR CapitalVC firmAustin, TXGrowthMedtech, Healthtech, AI, FintechNew fund, Aug 2026$100M (SEC Form D, 2025)4 Nov 20268 names · Unlock
Khosla VenturesVC firmMenlo Park, CAPre-seed, Seed, Series A, GrowthMedtech, AI, Consumer, B2BNew fund, Aug 2026$1.9B (SEC Form D, 2025)4 Nov 20268 names · Unlock
Digitalis VenturesVC firmNew York, NYSeedMedtech, Healthtech, BiotechPortfolio news, Nov 2026$862M (SEC Form ADV)5 Nov 20268 names, firm email · Unlock
Agetech CapitalVC firmAustin, TXMedtech, Healthtech, AI, FintechNew fund, Sep 2026$3M (SEC Form D, 2026)4 Nov 20266 names · Unlock
Gore Range CapitalVC firmSouthlake, TXSeedMedtech, Healthtech, BiotechNew deal, Aug 2026$250M (SEC Form D, 2026)4 Nov 20261 name, firm email · Unlock
Town Hall VenturesVC firmNew York, NYGrowthMedtech, Healthtech, ImpactNew deal, Sep 2026$400M (SEC Form D, 2025)5 Nov 20268 names · Unlock
Echo Health VenturesCorporate VCDurham, NCGrowthMedtech, HealthtechPortfolio news, Sep 2026$518M (SEC Form ADV)5 Nov 20262 names · Unlock
Health Velocity CapitalVC firmSan Mateo, CAMedtech, Healthtech, SaaSNew fund, Aug 2026$300M (SEC Form D, 2025)4 Nov 20265 names · Unlock
Cybernetix VenturesVC firmBoston, MAPre-seed, Seed, Series AMedtech, Robotics, Industrial Tech, LogisticsNew fund, Aug 2026$100M (SEC Form D, 2025)4 Nov 20262 names · Unlock
Hatteras Venture PartnersVC firmDurham, NCSeedMedtech, Healthtech, BiotechNew fund, Oct 2026$250M (SEC Form D, 2023)4 Nov 20268 names · Unlock
7wire VenturesVC firmChicago, ILSeedMedtech, Healthtech, AI, SaaSNew fund, Oct 2026$300M (SEC Form D, 2022)4 Nov 20268 names · Unlock
Safar PartnersVC firmCambridge, MASeedMedtech, Healthtech, Industrial Tech, BiotechNew deal, Aug 2026$300M (SEC Form D, 2023)4 Nov 20263 names, firm email · Unlock
ClareviaVC firmMadison, WIMedtech, Healthtech, BiotechNew deal, May 2026$100M (SEC Form D, 2023)5 Nov 20268 names · Unlock
HealthX VenturesVC firmMadison, WISeedMedtech, Healthtech, AI, SaaSNew deal, Sep 2026$100M (SEC Form D, 2023)5 Nov 20268 names, firm email · Unlock
1540 VenturesVC firmNew York, NYMedtech, HealthtechNew fund, Oct 2026$50M (SEC Form D, 2026)4 Nov 20261 name, firm email · Unlock
SHD PartnersVC firmDallas, TXSeed, Series AMedtech, Healthtech, BiotechPortfolio news, Nov 2026$61M (SEC Form ADV)5 Nov 20266 names, firm email · Unlock
InspiredVC firmNew York, NYSeedMedtech, AI, Fintech, GeneralistNew fund, Oct 2026$450M (SEC Form D, 2026)4 Nov 20268 names · Unlock
HC9 VenturesVC firmHavertown, PASeed, Series AMedtech, Healthtech, AI, FintechNew fund, Oct 2026$85M (SEC Form D, 2025)4 Nov 20263 names · Unlock
25Madison VenturesVC firmNew York, NYPre-seed, Seed, Series AMedtech, Healthtech, AI, LogisticsNew fund, Oct 2026$50M (SEC Form D, 2026)4 Nov 20268 names, firm email · Unlock
Meridian StreetVC firmNew York, NYPre-seedMedtech, Healthtech, AI, FintechNew fund, Aug 2026$85M (SEC Form D, 2026)4 Nov 20268 names · Unlock
Great Oaks Venture CapitalVC firmNew York, NYPre-seed, Seed, Series AMedtech, Healthtech, Generalist, SaaSPortfolio news, Sep 2026$20M (SEC Form ADV)5 Nov 20266 names · Unlock
Equal Opportunity VenturesVC firmCambridge, MAPre-seedMedtech, Healthtech, Fintech, Food and BeverageNew deal, Apr 2026$152M (SEC Form ADV)5 Nov 20268 names · Unlock
1616 VenturesVC firmNashville, TNPre-seedMedtech, Healthtech, SaaSNew fund, Aug 2026$150M (SEC Form D, 2026)4 Nov 20261 name · Unlock

You are seeing 25 of 350. The full list adds 325 more firms and 1,731 named decision-makers.

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How these 350 break down

By US state

US stateOn this listShare
California9226%
New York5315%
Massachusetts3711%
Texas247%
Illinois123%
Florida123%
Tennessee113%
Pennsylvania93%
Washington82%
Maryland72%

Full lists, each with its own row count: Medtech investors in California (92)Medtech investors in New York (53)Medtech investors in Massachusetts (37)Medtech investors in Texas (25)

By stage

StageOn this listShare
Pre-Seed9226%
Seed20458%
Series A7622%
Series B3610%
Growth6920%

Stage is our research. A firm can back more than one stage.

Full lists, each with its own row count: Pre-seed medtech investors in the US (95)Seed medtech investors in the US (205)Series A medtech investors in the US (76)Series B medtech investors in the US (36)Growth-stage medtech investors in the US (69)

By type

TypeOn this listShare
VC firm34298%
Corporate VC51%
Fund manager31%

Method and limits

Source
348 of the 350 rows carry an SEC filing (Form D or Form ADV). 347 of the 350 have a website we checked; the other 3 rest on the filing or register entry alone. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
Inclusion rule
Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. This list holds VC firms, fund managers and corporate venture arms; accelerators and angel networks are in their own lists. Sector: the firm states medtech and medical devices as a focus on its own site, or we observed it in the firm's portfolio.
Order
Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (35: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (25; half of that when the sector is stated only), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (15) and completeness of the public record (10). Regional focus is our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
Last refreshed
November 2026. Rows on this list were checked between 4 Nov 2026 and 6 Nov 2026.
Fill rates
Of 350 rows: stage 282, sector 350, fund size 316, website 347. In the paid file: named decision-makers on 334 rows, firm email on 112, LinkedIn page on 189, check size on 23.
Corrections
Email [email protected] or use the update form. We act within 5 working days.

How we verify

Questions

How many medtech venture capital firms in the US are there?

We list 350 as of November 2026. 178 of the 350 have a fund filing or a dated deal in the last 12 months. The cities with the most are New York (47), San Francisco (25) and Boston (19).

Which medtech venture capital firms in the US raised a new fund in the last 12 months?

124 of the 350 have a fund filing dated in the last 12 months. The most recent on this list are Reveille (Nov 2026), 25Madison Ventures (Oct 2026) and SJF Ventures (Oct 2026).

What is the typical fund size of medtech venture capital firms in the US?

The median fund size on file for this list is $60M, across the 243 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 107 do not disclose a size there.

Which stage do most medtech venture capital firms in the US back?

Of the 282 with a stage on file, seed (204), pre-seed (92) and Series A (76). A firm can back more than one stage, and 68 rows have no stage on file yet.

Where does the data on medtech venture capital firms in the US come from and how often is it updated?

348 of the 350 rows have an SEC filing on file (Form D or Form ADV) and 2 were checked on the firm's own website or an official register. Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 6 Nov 2026 at the latest. The whole file is re-verified twice a year.

Can I download the list of medtech venture capital firms in the US as a spreadsheet?

Yes. The file holds all 350 rows in Excel and CSV, with 1,731 named decision-makers and 112 firm emails, for $197 one-time as part of US Complete. 25 rows are free on this page.

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