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Updated November 2026

322 deep tech venture capital firms in the US

We list 322 deep tech venture capital firms in the US as of November 2026: 318 have an SEC filing on file and 4 were checked on the firm's own website or an official register, and the list was last checked on 7 Nov 2026. The cities with the most head offices on this list are New York (38), San Francisco (37) and Palo Alto (21).

322firms
196with a fund filing or dated deal in the last 12 months
$60Mmedian fund size on file (SEC Form D, 229 firms)
1,566named decision-makers on file

Top 10 deep tech venture capital firms in the US, ranked by recent fund activity

Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (35: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (25; half of that when the sector is stated only), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (15) and completeness of the public record (10). Regional focus is our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.

  1. NSV

    Type: VC firm · HQ: Greenwich, CT · Stages: Seed, Late stage · Focus: Deep Tech, Healthtech, AI, Semiconductor · Latest activity: Portfolio news, Oct 2026 · Private fund assets: $990M (SEC Form ADV)

    Portfolio news dated Oct 2026; $990M on file (SEC Form ADV); 26% of its observed portfolio is deep tech; names the US as where it invests; 5 named decision-makers on file.

  2. New Science Ventures

    Type: VC firm · HQ: United States · Stages: Seed, Growth, Late stage · Focus: Deep Tech, Healthtech, AI, Semiconductor · Latest activity: Portfolio news, Oct 2026 · Fund size or assets: $1.0B (own site)

    Portfolio news dated Oct 2026; $1.0B on file (own site); states deep tech as a focus; names the US as where it invests; 6 named decision-makers on file.

  3. Madrona

    Type: VC firm · HQ: Seattle, WA · Stages: Pre-seed, Seed, Series A, Series B, Growth · Focus: Deep Tech, AI, Biotech, Consumer · Latest activity: New deal, Oct 2026 · Fund size on file: $490M (SEC Form D, 2025)

    Dated new deal in Oct 2026; $490M fund on file (SEC Form D, 2025); states deep tech as a focus; names the US as where it invests; 8 named decision-makers on file.

  4. WYO VC

    Type: VC firm · HQ: Cody, WY · Focus: Deep Tech, Healthtech, AI, Energy · Latest activity: New fund, Aug 2026 · Fund size on file: $40M (SEC Form D, 2024)

    Latest fund filing dated Aug 2026; $40M fund on file (SEC Form D, 2024); 50% of its observed portfolio is deep tech; 3 named decision-makers on file.

  5. SOSV

    Type: VC firm · HQ: United States · Stages: Pre-seed · Focus: Deep Tech, Climate Tech, Healthtech, Biotech · Latest activity: Portfolio news, Nov 2026 · Fund size on file: $131M (SEC Form D, 2022)

    Portfolio news dated Nov 2026; $131M fund on file (SEC Form D, 2022); states deep tech as a focus; names the US as where it invests; 8 named decision-makers on file.

  6. Inflection

    Type: VC firm · HQ: Framingham, MA · Stages: Pre-seed, Seed · Focus: Deep Tech, AI, Space, Defense Tech · Latest activity: New fund, Sep 2026 · Fund size on file: $50M (SEC Form D, 2026)

    Latest fund filing dated Sep 2026; $50M fund on file (SEC Form D, 2026); 27% of its observed portfolio is deep tech; names the US as where it invests; 3 named decision-makers on file.

  7. Gft Ventures

    Type: VC firm · HQ: Palo Alto, CA · Stages: Seed, Series A · Focus: Deep Tech, AI, Marketing Tech, Media · Latest activity: Portfolio news, Aug 2026 · Fund size on file: $117M (SEC Form D, 2021)

    Portfolio news dated Aug 2026; $117M fund on file (SEC Form D, 2021); states deep tech as a focus; names the US as where it invests; 6 named decision-makers on file.

  8. Light Ray Ventures

    Type: VC firm · HQ: New York, NY · Stages: Seed · Focus: Deep Tech, Robotics, Industrial Tech, Climate Tech · Latest activity: New deal, Oct 2026 · Fund size on file: $21M (SEC Form D, 2023)

    Dated new deal in Oct 2026; $21M fund on file (SEC Form D, 2023); 29% of its observed portfolio is deep tech; names the US as where it invests; 3 named decision-makers on file.

  9. Safar Partners

    Type: VC firm · HQ: Cambridge, MA · Stages: Seed · Focus: Deep Tech, Healthtech, Industrial Tech, Biotech · Latest activity: New deal, Aug 2026 · Fund size on file: $300M (SEC Form D, 2023)

    Dated new deal in Aug 2026; $300M fund on file (SEC Form D, 2023); 17% of its observed portfolio is deep tech; names the US as where it invests; 3 named decision-makers on file.

  10. Ecosphere Ventures

    Type: VC firm · HQ: Sugar Land, TX · Stages: Pre-seed, Seed · Focus: Deep Tech, Energy, Climate Tech, Industrial Tech · Latest activity: New fund, Sep 2026 · Fund size on file: $10M (SEC Form D, 2026)

    Latest fund filing dated Sep 2026; $10M fund on file (SEC Form D, 2026); 32% of its observed portfolio is deep tech; names the US as where it invests; 8 named decision-makers on file.

First 25 of 322 deep tech venture capital firms in the US

InvestorTypeHQStagesour researchFocusour researchLatest fund or dealFund sizeas filed or statedCheckedContacts
NSVVC firmGreenwich, CTSeed, Late stageDeep Tech, Healthtech, AI, SemiconductorPortfolio news, Oct 2026$990M (SEC Form ADV)5 Nov 20265 names · Unlock
New Science VenturesVC firmUnited StatesSeed, Growth, Late stageDeep Tech, Healthtech, AI, SemiconductorPortfolio news, Oct 2026$1.0B (own site)5 Nov 20266 names · Unlock
MadronaVC firmSeattle, WAPre-seed, Seed, Series A, Series B, GrowthDeep Tech, AI, Biotech, ConsumerNew deal, Oct 2026$490M (SEC Form D, 2025)5 Nov 20268 names · Unlock
WYO VCVC firmCody, WYDeep Tech, Healthtech, AI, EnergyNew fund, Aug 2026$40M (SEC Form D, 2024)4 Nov 20263 names · Unlock
SOSVVC firmUnited StatesPre-seedDeep Tech, Climate Tech, Healthtech, BiotechPortfolio news, Nov 2026$131M (SEC Form D, 2022)4 Nov 20268 names · Unlock
InflectionVC firmFramingham, MAPre-seed, SeedDeep Tech, AI, Space, Defense TechNew fund, Sep 2026$50M (SEC Form D, 2026)4 Nov 20263 names, firm email · Unlock
Gft VenturesVC firmPalo Alto, CASeed, Series ADeep Tech, AI, Marketing Tech, MediaPortfolio news, Aug 2026$117M (SEC Form D, 2021)5 Nov 20266 names, firm email · Unlock
Light Ray VenturesVC firmNew York, NYSeedDeep Tech, Robotics, Industrial Tech, Climate TechNew deal, Oct 2026$21M (SEC Form D, 2023)5 Nov 20263 names, firm email · Unlock
Safar PartnersVC firmCambridge, MASeedDeep Tech, Healthtech, Industrial Tech, BiotechNew deal, Aug 2026$300M (SEC Form D, 2023)4 Nov 20263 names, firm email · Unlock
Ecosphere VenturesVC firmSugar Land, TXPre-seed, SeedDeep Tech, Energy, Climate Tech, Industrial TechNew fund, Sep 2026$10M (SEC Form D, 2026)4 Nov 20268 names · Unlock
Soma CapitalVC firmMiami Beach, FLSeedDeep Tech, AI, Fintech, SaaSNew fund, Oct 2026$200M (SEC Form D, 2023)4 Nov 20268 names · Unlock
Energy Impact PartnersVC firmUnited States (London office)Seed, Series A, Series B, GrowthDeep Tech, Energy, Climate Tech, AIPortfolio news, Nov 2026$4.5B (own site)5 Nov 20268 names · Unlock
Balerion Space VenturesVC firmDallas, TXDeep Tech, Space, Defense Tech, Industrial TechNew fund, Oct 2026$80M (SEC Form D, 2024)4 Nov 20268 names, firm email · Unlock
Qubits VenturesVC firmPasadena, CASeedDeep Tech, Quantum, AINew fund, Oct 2026$50M (SEC Form D, 2025)4 Nov 20268 names, firm email · Unlock
Cambium CapitalVC firmHighland, MDSeedDeep Tech, AI, Semiconductor, CybersecurityNew deal, Sep 2026$74M (SEC Form D, 2021)4 Nov 20266 names, firm email · Unlock
Toyota VenturesCorporate VCLos Altos, CASeed, Series ADeep Tech, AI, Energy, Climate TechPortfolio news, Oct 2026$928M (SEC Form ADV)5 Nov 2026LinkedIn page · Unlock
TreeoVCVC firmPompano Beach, FLPre-seed, SeedDeep Tech, AI, Healthtech, RoboticsNew fund, Aug 2026$9M (SEC Form D, 2023)4 Nov 20263 names, firm email · Unlock
True VenturesVC firmPalo Alto, CAPre-seed, SeedDeep Tech, AI, Fintech, ConsumerNew fund, Sep 2026$800M (SEC Form D, 2022)4 Nov 20268 names · Unlock
1517 FundVC firmTelluride, COPre-seedDeep Tech, AI, Edtech, SaaSNew fund, Sep 2026$43M (SEC Form D, 2025)4 Nov 20262 names, firm email · Unlock
Hallstone VenturesVC firmHollywood, CASeedDeep Tech, Space, Robotics, MediaNew fund, Oct 2026$11M (SEC Form D, 2025)4 Nov 20265 names · Unlock
Aurelia FoundryVC firmDenver, COSeed, Series ADeep Tech, Space, Mobility, Climate TechNew fund, Oct 2026$75M (SEC Form D, 2023)4 Nov 20265 names, firm email · Unlock
Side Door MichiganVC firmFernandina Beach, FLSeedDeep Tech, Space, Mobility, Crypto and Web3New fund, Sep 2026$30M (SEC Form D, 2023)4 Nov 20268 names · Unlock
Bison VenturesVC firmSan Francisco, CAPre-seed, Seed, Series A, Series BDeep Tech, AI, Healthtech, EnergyNew fund, Oct 2026$160M (SEC Form D, 2025)4 Nov 20262 names, firm email · Unlock
Scout VenturesVC firmAustin, TXSeedDeep Tech, Defense Tech, AI, RoboticsNew deal, May 2026$125M (SEC Form D, 2022)4 Nov 20268 names · Unlock
Khosla VenturesVC firmMenlo Park, CAPre-seed, Seed, Series A, GrowthDeep Tech, AI, Consumer, B2BNew fund, Aug 2026$1.9B (SEC Form D, 2025)4 Nov 20268 names · Unlock

You are seeing 25 of 322. The full list adds 297 more firms and 1,566 named decision-makers.

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How these 322 break down

By US state

US stateOn this listShare
California13843%
New York4213%
Massachusetts206%
Florida196%
Texas155%
Colorado93%
Illinois93%
Washington82%
Connecticut62%
Michigan41%

By stage

StageOn this listShare
Pre-Seed11435%
Seed20564%
Series A7323%
Series B4113%
Growth4313%

Stage is our research. A firm can back more than one stage.

By type

TypeOn this listShare
VC firm32099%
Corporate VC10%
Fund manager10%

Method and limits

Source
318 of the 322 rows carry an SEC filing (Form D or Form ADV). 321 of the 322 have a website we checked; the other 1 rests on the filing or register entry alone. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
Inclusion rule
Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. This list holds VC firms, fund managers and corporate venture arms; accelerators and angel networks are in their own lists. Sector: the firm states deep tech as a focus on its own site, or we observed it in the firm's portfolio.
Order
Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (35: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (25; half of that when the sector is stated only), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (15) and completeness of the public record (10). Regional focus is our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
Last refreshed
November 2026. Rows on this list were checked between 4 Nov 2026 and 7 Nov 2026.
Fill rates
Of 322 rows: stage 258, sector 322, fund size 279, website 321. In the paid file: named decision-makers on 304 rows, firm email on 117, LinkedIn page on 164, check size on 25.
Corrections
Email [email protected] or use the update form. We act within 5 working days.

How we verify

Questions

How many deep tech venture capital firms in the US are there?

We list 322 as of November 2026. 196 of the 322 have a fund filing or a dated deal in the last 12 months. The cities with the most are New York (38), San Francisco (37) and Palo Alto (21).

Which deep tech venture capital firms in the US raised a new fund in the last 12 months?

150 of the 322 have a fund filing dated in the last 12 months. The most recent on this list are Reveille (Nov 2026), Decisive Point VENTURES (Nov 2026) and Future Ventures (Oct 2026).

What is the typical fund size of deep tech venture capital firms in the US?

The median fund size on file for this list is $60M, across the 229 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 93 do not disclose a size there.

Which stage do most deep tech venture capital firms in the US back?

Of the 258 with a stage on file, seed (205), pre-seed (114) and Series A (73). A firm can back more than one stage, and 64 rows have no stage on file yet.

Where does the data on deep tech venture capital firms in the US come from and how often is it updated?

318 of the 322 rows have an SEC filing on file (Form D or Form ADV) and 4 were checked on the firm's own website or an official register. Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 7 Nov 2026 at the latest. The whole file is re-verified twice a year.

Can I download the list of deep tech venture capital firms in the US as a spreadsheet?

Yes. The file holds all 322 rows in Excel and CSV, with 1,566 named decision-makers and 117 firm emails, for $197 one-time as part of US Complete. 25 rows are free on this page.

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