25 venture capital firms in San Diego
We list 25 venture capital firms in San Diego as of November 2026: each has an SEC filing on file, and the list was last checked on 6 Nov 2026. The cities with the most head offices on this list are San Diego (11), La Jolla (6) and Encinitas (3).
Top 10 venture capital firms in San Diego, ranked by recent fund activity
Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (50: full marks within 3 months, then stepping down at 6, 12 and 24 months), size of the fund on file on a log scale (35) and completeness of the public record (15). It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.
IceNine Capital
Type: VC firm · HQ: San Diego, CA · Stages: Seed · Focus: Space, Defense Tech, Industrial Tech, Deep Tech · Latest activity: New fund, Oct 2026
Latest fund filing dated Oct 2026; backs seed; 5 named decision-makers on file.
Vesta Ventures
Type: VC firm · HQ: Encinitas, CA · Focus: Proptech, AI, Fintech, SaaS · Latest activity: New fund, Jul 2026 · Fund size on file: $10M (SEC Form D, 2026)
Latest fund filing dated Jul 2026; $10M fund on file (SEC Form D, 2026); 5 named decision-makers on file.
Harpoon Ventures
Type: VC firm · HQ: San Diego, CA · Focus: AI, Mobility, Space, Defense Tech · Latest activity: New fund, Feb 2026 · Fund size on file: $140M (SEC Form D, 2026)
Latest fund filing dated Feb 2026; $140M fund on file (SEC Form D, 2026); 3 named decision-makers on file.
TVC Capital
Type: VC firm · HQ: La Jolla, CA · Stages: Growth · Focus: Healthtech, SaaS, B2B, AI · Latest activity: Portfolio news, Jan 2025 · Private fund assets: $308M (SEC Form ADV)
Portfolio news dated Jan 2025; $308M on file (SEC Form ADV); backs growth-stage; 4 named decision-makers on file.
Avalon BioVentures
Type: VC firm · HQ: La Jolla, CA · Stages: Pre-seed · Focus: Biotech, Healthtech, Space · Latest activity: Portfolio news, Nov 2024 · Fund size on file: $200M (SEC Form D, 2021)
Portfolio news dated Nov 2024; $200M fund on file (SEC Form D, 2021); backs pre-seed; 8 named decision-makers on file.
Behind Genius Ventures
Type: VC firm · HQ: San Diego, CA · Stages: Pre-seed, Seed · Focus: AI, Media, Developer Tools, Future of Work · Latest activity: New fund, Jul 2026 · Fund size on file: $2M (SEC Form D, 2026)
Latest fund filing dated Jul 2026; $2M fund on file (SEC Form D, 2026); backs pre-seed, seed; 5 named decision-makers on file.
Channel Equity Partners
Type: VC firm · HQ: San Diego, CA · Stages: Growth · Focus: SaaS, B2B, AI · Latest activity: New fund, Apr 2026 · Fund size on file: $20M (SEC Form D, 2024)
Latest fund filing dated Apr 2026; $20M fund on file (SEC Form D, 2024); backs growth-stage; 2 named decision-makers on file.
Kaleida Capital
Type: VC firm · HQ: San Diego, CA · Focus: Healthtech, AI, Biotech, Deep Tech · Latest activity: New fund, Jun 2026
Latest fund filing dated Jun 2026; 4 named decision-makers on file.
Radicle Growth
Type: VC firm · HQ: San Diego, CA · Focus: Agritech, AI, Healthtech, Climate Tech · Latest activity: New deal, Jun 2026
Dated new deal in Jun 2026; 2 named decision-makers on file.
Newtown Partners
Type: VC firm · HQ: San Diego, CA · Stages: Seed, Series A · Focus: Logistics, Fintech · Latest activity: Portfolio news, Oct 2025 · Private fund assets: $28M (SEC Form ADV)
Portfolio news dated Oct 2025; $28M on file (SEC Form ADV); backs seed, Series A; 1 named decision-maker on file.
First 12 of 25 venture capital firms in San Diego
| Investor | Type | HQ | Stagesour research | Focusour research | Latest fund or deal | Fund sizeas filed or stated | Checked | Contacts |
|---|---|---|---|---|---|---|---|---|
| IceNine Capital | VC firm | San Diego, CA | Seed | Space, Defense Tech, Industrial Tech, Deep Tech | New fund, Oct 2026 | 4 Nov 2026 | 5 names, firm email · Unlock | |
| Vesta Ventures | VC firm | Encinitas, CA | Proptech, AI, Fintech, SaaS | New fund, Jul 2026 | $10M (SEC Form D, 2026) | 4 Nov 2026 | 5 names, firm email · Unlock | |
| Harpoon Ventures | VC firm | San Diego, CA | AI, Mobility, Space, Defense Tech | New fund, Feb 2026 | $140M (SEC Form D, 2026) | 4 Nov 2026 | 3 names · Unlock | |
| TVC Capital | VC firm | La Jolla, CA | Growth | Healthtech, SaaS, B2B, AI | Portfolio news, Jan 2025 | $308M (SEC Form ADV) | 5 Nov 2026 | 4 names, firm email · Unlock |
| Avalon BioVentures | VC firm | La Jolla, CA | Pre-seed | Biotech, Healthtech, Space | Portfolio news, Nov 2024 | $200M (SEC Form D, 2021) | 5 Nov 2026 | 8 names, firm email · Unlock |
| Behind Genius Ventures | VC firm | San Diego, CA | Pre-seed, Seed | AI, Media, Developer Tools, Future of Work | New fund, Jul 2026 | $2M (SEC Form D, 2026) | 4 Nov 2026 | 5 names · Unlock |
| Channel Equity Partners | VC firm | San Diego, CA | Growth | SaaS, B2B, AI | New fund, Apr 2026 | $20M (SEC Form D, 2024) | 4 Nov 2026 | 2 names · Unlock |
| Kaleida Capital | VC firm | San Diego, CA | Healthtech, AI, Biotech, Deep Tech | New fund, Jun 2026 | 4 Nov 2026 | 4 names, firm email · Unlock | ||
| Radicle Growth | VC firm | San Diego, CA | Agritech, AI, Healthtech, Climate Tech | New deal, Jun 2026 | 5 Nov 2026 | 2 names, firm email · Unlock | ||
| Newtown Partners | VC firm | San Diego, CA | Seed, Series A | Logistics, Fintech | Portfolio news, Oct 2025 | $28M (SEC Form ADV) | 5 Nov 2026 | 1 name, firm email · Unlock |
| Avalon Ventures | VC firm | La Jolla, CA | Pre-seed, Seed | Biotech | $236M (SEC Form ADV) | 5 Nov 2026 | 6 names, firm email · Unlock | |
| Clear Creek Investments, LLC | VC firm | Solana Beach, CA | Any stage | Climate Tech, Energy, Food and Beverage | $86M (SEC Form ADV) | 5 Nov 2026 | 2 names, firm email · Unlock |
You are seeing 12 of 25. The full list adds 13 more firms and 80 named decision-makers.
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How these 25 break down
By city
| City | On this list | Share |
|---|---|---|
| San Diego | 11 | 44% |
| La Jolla | 6 | 24% |
| Encinitas | 3 | 12% |
| Solana Beach | 2 | 8% |
By stage
| Stage | On this list | Share |
|---|---|---|
| Pre-Seed | 5 | 20% |
| Seed | 6 | 24% |
| Growth | 2 | 8% |
Stage is our research. A firm can back more than one stage.
By sector
| Sector | On this list | Share |
|---|---|---|
| AI | 10 | 40% |
| SaaS | 8 | 32% |
| Healthtech | 7 | 28% |
| Fintech | 5 | 20% |
| Biotech | 5 | 20% |
| Hardware | 4 | 16% |
| Space | 3 | 12% |
| Deep Tech | 3 | 12% |
| Medtech | 3 | 12% |
| Climate Tech | 3 | 12% |
| Defense Tech | 2 | 8% |
| Industrial Tech | 2 | 8% |
Sector is our research. A firm can carry more than one sector.
Method and limits
- Source
- All 25 rows carry an SEC filing (Form D or Form ADV). 15 of the 25 have a website we checked; the other 10 rest on the filing or register entry alone. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
- Inclusion rule
- Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. This list holds VC firms, fund managers and corporate venture arms; accelerators and angel networks are in their own lists. Place: head office in San Diego, matched on city and state.
- Order
- Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (50: full marks within 3 months, then stepping down at 6, 12 and 24 months), size of the fund on file on a log scale (35) and completeness of the public record (15). It is a measure of activity and fit, not of quality or returns.
- Last refreshed
- November 2026. Rows on this list were checked between 4 Nov 2026 and 6 Nov 2026.
- Fill rates
- Of 25 rows: stage 11, sector 16, fund size 20, website 15. In the paid file: named decision-makers on 23 rows, firm email on 10, LinkedIn page on 9, check size on 0.
- Corrections
- Email [email protected] or use the update form. We act within 5 working days.
Questions
How many VC firms are in San Diego?
We list 25 as of November 2026. 13 of the 25 have a fund filing or a dated deal in the last 12 months.
Which cities in San Diego have the most VC firms?
San Diego (11), La Jolla (6) and Encinitas (3).
Which San Diego VC funds filed with the SEC in the last 12 months?
11 of the 25 have a fund filing dated in the last 12 months. The most recent on this list are Trybe Sports (Oct 2026), IceNine Capital (Oct 2026) and GV (Sep 2026).
What stages do venture capital firms in San Diego back?
Of the 11 with a stage on file, seed (6), pre-seed (5) and growth-stage (2). A firm can back more than one stage, and 14 rows have no stage on file yet.
Where does the data on venture capital firms in San Diego come from and how often is it updated?
All 25 rows have an SEC filing on file (Form D or Form ADV). Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 6 Nov 2026 at the latest. The whole file is re-verified twice a year.
Can I download the list of venture capital firms in San Diego as a spreadsheet?
Yes. The file holds all 25 rows in Excel and CSV, with 80 named decision-makers and 10 firm emails, for $49 one-time. 12 rows are free on this page.
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