---
title: "48 Biotech Investors in Silicon Valley (Nov 2026)"
last_updated: "2026-11-06"
rows: "48"
free_rows: "24"
source: "SEC filings"
canonical: "https://theinvestordatabase.com/lists/biotech-investors-in-silicon-valley/"
---

# 48 biotech investors in Silicon Valley

We list 48 biotech investors in Silicon Valley as of November 2026: each has an SEC filing on file, and the list was last checked on 6 Nov 2026. The cities with the most head offices on this list are Palo Alto (16), Menlo Park (12) and San Mateo (6).

- 48 investors
- 23 with a fund filing or dated deal in the last 12 months
- $100M median fund size on file (SEC Form D, 32 firms)
- 250 named decision-makers on file

## First 24 of 48 biotech investors in Silicon Valley

| Investor | Type | HQ | Stages (our research) | Focus (our research) | Latest fund or deal | Fund size | Checked | Profile |
|---|---|---|---|---|---|---|---|---|
| Longitude Venture Partners | VC firm | Menlo Park, CA | Growth | Biotech, Healthtech, Medtech | New deal, Jun 2026 | $600M (SEC Form D, 2022) | 2026-11-05 | https://theinvestordatabase.com/investors/longitude-venture-partners/ |
| TCGX | VC firm | Palo Alto, CA |  | Biotech, Healthtech | New fund, Oct 2026 | $600M (SEC Form D, 2026) | 2026-11-04 | https://theinvestordatabase.com/investors/tcgx/ |
| Mitsui & Co. Global Investment, Inc. | Corporate VC | Menlo Park, CA |  | Biotech, Healthtech, AI, Industrial Tech | Portfolio news, Jun 2026 | $142M (SEC Form ADV) | 2026-11-05 | https://theinvestordatabase.com/investors/mitsui-co-global-investment-inc/ |
| Felicis | VC firm | Menlo Park, CA | Seed, Series A | Biotech, AI, Developer Tools, Healthtech | New deal, Oct 2026 | $900M (SEC Form D, 2025) | 2026-11-05 | https://theinvestordatabase.com/investors/felicis/ |
| True Ventures | VC firm | Palo Alto, CA | Pre-seed, Seed | Biotech, AI, Fintech, Deep Tech | New fund, Sep 2026 | $800M (SEC Form D, 2022) | 2026-11-04 | https://theinvestordatabase.com/investors/true-ventures/ |
| Future Ventures | VC firm | Los Altos, CA | Seed | Biotech, Healthtech, AI, Energy | New fund, Oct 2026 | $200M (SEC Form D, 2021) | 2026-11-04 | https://theinvestordatabase.com/investors/future-ventures/ |
| Sofinnova | VC firm | Menlo Park, CA |  | Biotech, Healthtech | New fund, Jun 2026 | $550M (SEC Form D, 2024) | 2026-11-04 | https://theinvestordatabase.com/investors/sofinnova/ |
| DCVC | VC firm | Palo Alto, CA |  | Biotech, Energy, Healthtech, AI | New fund, Oct 2026 | $800M (SEC Form D, 2025) | 2026-11-04 | https://theinvestordatabase.com/investors/dcvc/ |
| Draper Associates | VC firm | San Mateo, CA | Pre-seed, Seed, Series A | Biotech, AI, Fintech, Healthtech | New fund, Oct 2026 | $301M (SEC Form D, 2025) | 2026-11-04 | https://theinvestordatabase.com/investors/draper-associates/ |
| 3i Partners | VC firm | Los Altos, CA | Pre-seed, Seed | Biotech, Mobility, Healthtech, Deep Tech | New fund, May 2026 | $24M (SEC Form D, 2025) | 2026-11-05 | https://theinvestordatabase.com/investors/3i-partners-los-altos/ |
| Nanodimension | VC firm | Woodside, CA | Any stage | Biotech, Healthtech, Deep Tech |  | $594M (SEC Form ADV) | 2026-11-05 | https://theinvestordatabase.com/investors/nanodimension/ |
| Andreessen Horowitz (a16z) | VC firm | Menlo Park, CA | Seed, Series A, Series B, Growth | Biotech, AI, Defense Tech, Healthtech | New fund, Aug 2026 |  | 2026-11-04 | https://theinvestordatabase.com/investors/andreessen-horowitz-a16z/ |
| Phoenix Venture Partners | VC firm | San Mateo, CA | Seed | Biotech, AI, Healthtech, Energy | Portfolio news, Jul 2026 | $109M (SEC Form D, 2021) | 2026-11-05 | https://theinvestordatabase.com/investors/phoenix-venture-partners/ |
| Pear Ventures | VC firm | Menlo Park, CA | Pre-seed, Seed | Biotech, AI, Fintech, Healthtech | New fund, Oct 2026 | $410M (SEC Form D, 2022) | 2026-11-04 | https://theinvestordatabase.com/investors/pear-ventures/ |
| Frazier Life Sciences | VC firm | Palo Alto, CA | Pre-seed, Seed, Series A, Series B, Growth | Biotech, Healthtech | New fund, Mar 2025 | $7.0B (SEC Form ADV) | 2026-11-05 | https://theinvestordatabase.com/investors/frazier-life-sciences/ |
| ShangBay Capital | VC firm | Palo Alto, CA | Seed | Biotech, Healthtech, Medtech | New deal, Jan 2025 | $48M (SEC Form D, 2021) | 2026-11-05 | https://theinvestordatabase.com/investors/shangbay-capital/ |
| Calculus VC | VC firm | Foster City, CA | Series A, Series B | Biotech, AI, Deep Tech, Healthtech | New deal, Aug 2026 | $1M (SEC Form D, 2025) | 2026-11-04 | https://theinvestordatabase.com/investors/calculus-vc/ |
| DC Global Ventures | VC firm | Menlo Park, CA | Seed, Growth | Biotech, Healthtech, Industrial Tech, Medtech |  | $2.7B (SEC Form ADV) | 2026-11-05 | https://theinvestordatabase.com/investors/dc-global-ventures/ |
| ACVC Partners | VC firm | Palo Alto, CA | Seed | Biotech, AI, Deep Tech, Mobility | New fund, Dec 2024 | $50M (SEC Form D, 2024) | 2026-11-05 | https://theinvestordatabase.com/investors/acvc-partners/ |
| Innovation Endeavors | VC firm | Palo Alto, CA | Seed | Biotech, AI, Robotics, Healthtech | New deal, Feb 2026 | $600M (SEC Form D, 2023) | 2026-11-05 | https://theinvestordatabase.com/investors/innovation-endeavors/ |
| Dalena Capital | VC firm | Palo Alto, CA | Seed | Biotech, Healthtech | New fund, May 2026 | $5M (SEC Form D, 2025) | 2026-11-04 | https://theinvestordatabase.com/investors/dalena-capital/ |
| NTI | VC firm | Mountain View, CA | Seed, Series A | Biotech, Healthtech, Mobility, Medtech |  | $56M (SEC Form ADV) | 2026-11-05 | https://theinvestordatabase.com/investors/nti/ |
| Fusion Fund | VC firm | Palo Alto, CA | Pre-seed, Seed, Series A | Biotech, AI, Healthtech, Industrial Tech | New fund, Jun 2024 | $526M (SEC Form ADV) | 2026-11-05 | https://theinvestordatabase.com/investors/fusion-fund/ |
| Better Capital | VC firm | Santa Clara, CA | Pre-seed, Seed | Biotech, AI, Healthtech, Climate Tech | Portfolio news, Mar 2026 | $60M (SEC Form D, 2022) | 2026-11-05 | https://theinvestordatabase.com/investors/better-capital/ |

You are seeing 24 of 48. The full list adds 24 more investors and 250 named decision-makers.

Get all 48 investors and 250 named contacts, $49, one-time: https://theinvestordatabase.com/buy/list/biotech-investors-in-silicon-valley
This page: https://theinvestordatabase.com/lists/biotech-investors-in-silicon-valley/

## Method and limits
- Source: All 48 rows carry an SEC filing (Form D or Form ADV). 47 of the 48 have a website we checked; the other 1 rests on the filing or register entry alone. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
- Inclusion rule: Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. Sector: the firm states biotech and life sciences as a focus on its own site, or we observed it in the firm's portfolio. Place: head office in Silicon Valley, matched on city and state.
- Order: Activity score out of 100: recency of the latest fund filing or dated deal (35: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (25; half of that when the sector is stated only), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (15) and completeness of the public record (10). Regional focus is our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
- Fill rates: Of 48 rows: stage 37, sector 48, fund size 44, website 47. In the paid file: named decision-makers on 45 rows, firm email on 10, LinkedIn page on 21, check size on 0.

## Questions
### How many biotech investors in Silicon Valley are there?
We list 48 as of November 2026. 23 of the 48 have a fund filing or a dated deal in the last 12 months. The cities with the most are Palo Alto (16), Menlo Park (12) and San Mateo (6).

### Which biotech investors in Silicon Valley raised a new fund in the last 12 months?
16 of the 48 have a fund filing dated in the last 12 months. The most recent on this list are Future Ventures (Oct 2026), Draper Associates (Oct 2026) and Pear Ventures (Oct 2026).

### What is the typical fund size of biotech investors in Silicon Valley?
The median fund size on file for this list is $100M, across the 32 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 16 do not disclose a size there.

### How do I contact biotech investors in Silicon Valley?
The paid file holds 250 named decision-makers across 45 of these 48 and a firm email for 10. We publish the address a firm lists itself, never a personal email. Each free row links to a profile with the firm's website.

### Where does the data on biotech investors in Silicon Valley come from?
All 48 rows have an SEC filing on file (Form D or Form ADV). Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 6 Nov 2026 at the latest. The whole file is re-verified twice a year.