108 biotech investors in California
We list 108 biotech investors in California as of November 2026: each has an SEC filing on file, and the list was last checked on 6 Nov 2026. The cities with the most head offices on this list are San Francisco (27), Palo Alto (16) and Menlo Park (12).
Top 5 biotech investors in California, ranked by recent fund activity
Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (35: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (25; half of that when the sector is stated only), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (15) and completeness of the public record (10). Regional focus is our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.
Longitude Venture Partners
Type: VC firm · HQ: Menlo Park, CA · Stages: Growth · Focus: Biotech, Healthtech, Medtech · Latest activity: New deal, Jun 2026 · Fund size on file: $600M (SEC Form D, 2022)
Dated new deal in Jun 2026; $600M fund on file (SEC Form D, 2022); 80% of its observed portfolio is biotech and life sciences; names the US as where it invests; 8 named decision-makers on file.
Vida Ventures
Type: VC firm · HQ: Los Angeles, CA · Focus: Biotech, Healthtech · Latest activity: New fund, Sep 2026 · Fund size on file: $750M (SEC Form D, 2021)
Latest fund filing dated Sep 2026; $750M fund on file (SEC Form D, 2021); 100% of its observed portfolio is biotech and life sciences; 8 named decision-makers on file.
TCGX
Type: VC firm · HQ: Palo Alto, CA · Focus: Biotech, Healthtech · Latest activity: New fund, Oct 2026 · Fund size on file: $600M (SEC Form D, 2026)
Latest fund filing dated Oct 2026; $600M fund on file (SEC Form D, 2026); 96% of its observed portfolio is biotech and life sciences; 8 named decision-makers on file.
Bison Ventures
Type: VC firm · HQ: San Francisco, CA · Stages: Pre-seed, Seed, Series A, Series B · Focus: Biotech, AI, Healthtech, Energy · Latest activity: New fund, Oct 2026 · Fund size on file: $160M (SEC Form D, 2025)
Latest fund filing dated Oct 2026; $160M fund on file (SEC Form D, 2025); 21% of its observed portfolio is biotech and life sciences; names the US as where it invests; 2 named decision-makers on file.
Mitsui & Co. Global Investment, Inc.
Type: Corporate VC · HQ: Menlo Park, CA · Focus: Biotech, Healthtech, AI, Industrial Tech · Latest activity: Portfolio news, Jun 2026 · Private fund assets: $142M (SEC Form ADV)
Portfolio news dated Jun 2026; $142M on file (SEC Form ADV); 38% of its observed portfolio is biotech and life sciences; names the US as where it invests; 3 named decision-makers on file.
First 25 of 108 biotech investors in California
| Investor | Type | HQ | Stagesour research | Focusour research | Latest fund or deal | Fund sizeas filed or stated | Checked | Contacts |
|---|---|---|---|---|---|---|---|---|
| Longitude Venture Partners | VC firm | Menlo Park, CA | Growth | Biotech, Healthtech, Medtech | New deal, Jun 2026 | $600M (SEC Form D, 2022) | 5 Nov 2026 | 8 names · Unlock |
| Vida Ventures | VC firm | Los Angeles, CA | Biotech, Healthtech | New fund, Sep 2026 | $750M (SEC Form D, 2021) | 4 Nov 2026 | 8 names, firm email · Unlock | |
| TCGX | VC firm | Palo Alto, CA | Biotech, Healthtech | New fund, Oct 2026 | $600M (SEC Form D, 2026) | 4 Nov 2026 | 8 names, firm email · Unlock | |
| Bison Ventures | VC firm | San Francisco, CA | Pre-seed, Seed, Series A, Series B | Biotech, AI, Healthtech, Energy | New fund, Oct 2026 | $160M (SEC Form D, 2025) | 4 Nov 2026 | 2 names, firm email · Unlock |
| Mitsui & Co. Global Investment, Inc. | Corporate VC | Menlo Park, CA | Biotech, Healthtech, AI, Industrial Tech | Portfolio news, Jun 2026 | $142M (SEC Form ADV) | 5 Nov 2026 | 3 names · Unlock | |
| Felicis | VC firm | Menlo Park, CA | Seed, Series A | Biotech, AI, Developer Tools, Healthtech | New deal, Oct 2026 | $900M (SEC Form D, 2025) | 5 Nov 2026 | 8 names · Unlock |
| True Ventures | VC firm | Palo Alto, CA | Pre-seed, Seed | Biotech, AI, Fintech, Deep Tech | New fund, Sep 2026 | $800M (SEC Form D, 2022) | 4 Nov 2026 | 8 names · Unlock |
| Lionheart Ventures | VC firm | San Francisco, CA | Biotech, Healthtech, Climate Tech, AI | New fund, Aug 2026 | $21M (SEC Form D, 2021) | 4 Nov 2026 | 8 names, firm email · Unlock | |
| How Women Invest | VC firm | Oakland, CA | Pre-seed, Seed, Series A, Series B | Biotech, Healthtech, AI, B2B | New fund, Sep 2026 | $12M (SEC Form D, 2026) | 4 Nov 2026 | 8 names · Unlock |
| Future Ventures | VC firm | Los Altos, CA | Seed | Biotech, Healthtech, AI, Energy | New fund, Oct 2026 | $200M (SEC Form D, 2021) | 4 Nov 2026 | 4 names · Unlock |
| Sofinnova | VC firm | Menlo Park, CA | Biotech, Healthtech | New fund, Jun 2026 | $550M (SEC Form D, 2024) | 4 Nov 2026 | 8 names, firm email · Unlock | |
| Breakout Ventures | VC firm | San Francisco, CA | Seed | Biotech, AI, Healthtech, Industrial Tech | New deal, Jun 2026 | $112M (SEC Form D, 2021) | 4 Nov 2026 | 6 names, firm email · Unlock |
| Refactor Capital | VC firm | Burlingame, CA | Seed | Biotech, AI, Healthtech, Energy | New fund, May 2026 | $50M (SEC Form D, 2021) | 4 Nov 2026 | 3 names · Unlock |
| Artis | VC firm | San Francisco, CA | Biotech, Healthtech, AI, Deep Tech | New fund, Jun 2026 | $300M (SEC Form D, 2022) | 4 Nov 2026 | 5 names · Unlock | |
| Avalon BioVentures | VC firm | La Jolla, CA | Pre-seed | Biotech, Healthtech, Space | Portfolio news, Nov 2024 | $200M (SEC Form D, 2021) | 5 Nov 2026 | 8 names, firm email · Unlock |
| Suncoast Ventures | VC firm | Walnut Creek, CA | Seed | Biotech, Healthtech, Medtech | New fund, Jul 2026 | $15M (SEC Form D, 2022) | 4 Nov 2026 | 8 names · Unlock |
| DCVC | VC firm | Palo Alto, CA | Biotech, Energy, Healthtech, AI | New fund, Oct 2026 | $800M (SEC Form D, 2025) | 4 Nov 2026 | 4 names · Unlock | |
| Draper Associates | VC firm | San Mateo, CA | Pre-seed, Seed, Series A | Biotech, AI, Fintech, Healthtech | New fund, Oct 2026 | $301M (SEC Form D, 2025) | 4 Nov 2026 | 8 names · Unlock |
| Column Group | VC firm | San Francisco, CA | Pre-seed | Biotech, Healthtech | New deal, Jan 2026 | $600M (SEC Form D, 2022) | 4 Nov 2026 | 8 names, firm email · Unlock |
| PsyMed Ventures | VC firm | Tahoma, CA | Seed | Biotech, Healthtech, AI, Medtech | New fund, Jun 2025 | $25M (SEC Form D, 2025) | 5 Nov 2026 | 5 names, firm email · Unlock |
| 3i Partners | VC firm | Los Altos, CA | Pre-seed, Seed | Biotech, Mobility, Healthtech, Deep Tech | New fund, May 2026 | $24M (SEC Form D, 2025) | 5 Nov 2026 | 8 names · Unlock |
| Nanodimension | VC firm | Woodside, CA | Any stage | Biotech, Healthtech, Deep Tech | $594M (SEC Form ADV) | 5 Nov 2026 | 5 names, firm email · Unlock | |
| Kapor Capital | VC firm | Oakland, CA | Pre-seed, Seed, Series A | Biotech, Edtech, Fintech, Healthtech | New deal, Jun 2026 | $125M (SEC Form D, 2021) | 5 Nov 2026 | 5 names · Unlock |
| OCV Partners | VC firm | Los Angeles, CA | Biotech, Healthtech, SaaS, Fintech | New deal, Jul 2026 | $1M (SEC Form D, 2024) | 5 Nov 2026 | 4 names · Unlock | |
| THP | VC firm | San Francisco, CA | Growth | Biotech, Healthtech, Industrial Tech, Medtech | Portfolio news, Apr 2026 | $79M (SEC Form D, 2022) | 5 Nov 2026 | 1 name, firm email · Unlock |
You are seeing 25 of 108. The full list adds 83 more investors and 531 named decision-makers.
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How these 108 break down
By metro area
| Metro area | On this list | Share |
|---|---|---|
| The San Francisco Bay Area | 88 | 81% |
| Silicon Valley | 48 | 44% |
| Los Angeles | 12 | 11% |
| San Diego | 5 | 5% |
Silicon Valley is counted inside the San Francisco Bay Area as well.
By city
| City | On this list | Share |
|---|---|---|
| San Francisco | 27 | 25% |
| Palo Alto | 16 | 15% |
| Menlo Park | 12 | 11% |
| San Mateo | 6 | 6% |
| Oakland | 5 | 5% |
| Los Angeles | 4 | 4% |
| Santa Clara | 4 | 4% |
| Los Altos | 3 | 3% |
| San Diego | 3 | 3% |
| Santa Monica | 3 | 3% |
By stage
| Stage | On this list | Share |
|---|---|---|
| Pre-Seed | 34 | 31% |
| Seed | 65 | 60% |
| Series A | 21 | 19% |
| Series B | 11 | 10% |
| Growth | 11 | 10% |
Stage is our research. A firm can back more than one stage.
By type
| Type | On this list | Share |
|---|---|---|
| VC firm | 105 | 97% |
| Corporate VC | 2 | 2% |
Method and limits
- Source
- All 108 rows carry an SEC filing (Form D or Form ADV). 103 of the 108 have a website we checked; the other 5 rest on the filing or register entry alone. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
- Inclusion rule
- Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. Sector: the firm states biotech and life sciences as a focus on its own site, or we observed it in the firm's portfolio. Place: head office in California.
- Order
- Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (35: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (25; half of that when the sector is stated only), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (15) and completeness of the public record (10). Regional focus is our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
- Last refreshed
- November 2026. Rows on this list were checked between 4 Nov 2026 and 6 Nov 2026.
- Fill rates
- Of 108 rows: stage 78, sector 108, fund size 94, website 103. In the paid file: named decision-makers on 101 rows, firm email on 32, LinkedIn page on 47, check size on 4.
- Corrections
- Email [email protected] or use the update form. We act within 5 working days.
Questions
How many biotech investors in California are there?
We list 108 as of November 2026. 48 of the 108 have a fund filing or a dated deal in the last 12 months. The cities with the most are San Francisco (27), Palo Alto (16) and Menlo Park (12).
Which biotech investors in California raised a new fund in the last 12 months?
32 of the 108 have a fund filing dated in the last 12 months. The most recent on this list are Future Ventures (Oct 2026), Draper Associates (Oct 2026) and Pear Ventures (Oct 2026).
What is the typical fund size of biotech investors in California?
The median fund size on file for this list is $89M, across the 70 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 38 do not disclose a size there.
How do I contact biotech investors in California?
The paid file holds 531 named decision-makers across 101 of these 108 and a firm email for 32. We publish the address a firm lists itself, never a personal email. Each free row links to a profile with the firm's website.
Where does the data on biotech investors in California come from?
All 108 rows have an SEC filing on file (Form D or Form ADV). Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 6 Nov 2026 at the latest. The whole file is re-verified twice a year.
Broader lists
Biotech venture capital firms in the US (297)Venture capital firms in California (1,038)
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